Activating Compound | Comment | Organism | Structure |
---|---|---|---|
cysteine | activation | Anas platyrhynchos | |
cysteine | activation | Columba sp. | |
cysteine | requirement | Anas platyrhynchos | |
cysteine | requirement | Columba sp. |
General Stability | Organism |
---|---|
stable to repeated freeze-thawing cycles | Columba sp. |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
additional information | no inhibition by F- with or without phosphate, adenosine, 2-, 3- or 5-adenylic acids, ADP, NAD+, NADH, deamino-NAD+, adenosine diphosphate ribose | Columba sp. |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.003 | - |
dephospho-CoA | pH 8.2, 37°C | Columba sp. |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
mitochondrion | - |
Anas platyrhynchos | 5739 | - |
mitochondrion | - |
Columba sp. | 5739 | - |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mg2+ | requirement | Anas platyrhynchos | |
Mg2+ | requirement | Columba sp. |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Anas platyrhynchos | - |
duck | - |
Columba sp. | - |
- |
- |
Purification (Comment) | Organism |
---|---|
4.5fold from liver acetone powder | Columba sp. |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Anas platyrhynchos | - |
liver | - |
Columba sp. | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
additional information | - |
- |
Columba sp. |
Storage Stability | Organism |
---|---|
-15°C, partially purified preparation, at least 2 months | Columba sp. |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + dephospho-CoA | specific | Anas platyrhynchos | ADP + CoA | - |
? | |
ATP + dephospho-CoA | specific | Columba sp. | ADP + CoA | - |
? | |
ATP + dephospho-CoA | ITP or ADP are no substrates | Anas platyrhynchos | ADP + CoA | - |
? | |
ATP + dephospho-CoA | ITP or ADP are no substrates | Columba sp. | ADP + CoA | - |
? | |
additional information | assay method: arsenolysis of dephospho-CoA, formation of CoA | Anas platyrhynchos | ? | - |
? | |
additional information | assay method: arsenolysis of dephospho-CoA, formation of CoA | Columba sp. | ? | - |
? |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
assay at | Anas platyrhynchos |
37 | - |
assay at | Columba sp. |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
8.2 | - |
assay at | Columba sp. |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
ATP | requirement | Anas platyrhynchos | |
ATP | requirement | Columba sp. |