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Literature summary for 2.7.1.221 extracted from

  • Sonnabend, M.S.; Klein, K.; Beier, S.; Angelov, A.; Kluj, R.; Mayer, C.; Gross, C.; Hofmeister, K.; Beuttner, A.; Willmann, M.; Peter, S.; Oberhettinger, P.; Schmidt, A.; Autenrieth, I.B.; Schuetz, M.; Bohn, E.
    Identification of drug resistance determinants in a clinical isolate of Pseudomonas aeruginosa by high-density transposon mutagenesis (2020), Antimicrob. Agents Chemother., 64, e01771-19 .
    View publication on PubMedView publication on EuropePMC
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Localization

Localization Comment Organism GeneOntology No. Textmining
cell wall
-
 Pseudomonas aeruginosa 5618
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + N-acetyl-D-muramate Pseudomonas aeruginosa
-
 ADP + N-acetyl-alpha-D-muramate 1-phosphate
-
 ?
ATP + N-acetyl-D-muramate Pseudomonas aeruginosa ID40
-
 ADP + N-acetyl-alpha-D-muramate 1-phosphate
-
 ?

Organism

Organism UniProt Comment Textmining
Pseudomonas aeruginosa
-
-
-
Pseudomonas aeruginosa ID40
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + N-acetyl-D-muramate
-
 Pseudomonas aeruginosa ADP + N-acetyl-alpha-D-muramate 1-phosphate
-
 ?
ATP + N-acetyl-D-muramate
-
 Pseudomonas aeruginosa ID40 ADP + N-acetyl-alpha-D-muramate 1-phosphate
-
 ?

Synonyms

Synonyms Comment Organism
amgK
-
 Pseudomonas aeruginosa
MurNAc/GlcNAc kinase
-
 Pseudomonas aeruginosa
N-acetylmuramate/N-acetylglucosamine kinase
-
 Pseudomonas aeruginosa

General Information

General Information Comment Organism
malfunction the deletion of the enzyme results in reduced resistance against fosfomycin Pseudomonas aeruginosa