KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.53 | - |
alpha-D-ribose 1-phosphate | presence of Mg2+, pH and temperature not specified in the publication | Thermococcus kodakarensis | |
0.53 | - |
alpha-D-ribose-1-phosphate | presence of Mg2+, pH not specified in the publication, temperature not specified in the publication | Thermococcus kodakarensis | |
4.19 | 8.37 | ADP | depending on the presence of Ca2+, pH and temperature not specified in the publication | Thermococcus kodakarensis | |
4.2 | - |
ADP | presence of Ca2+, pH not specified in the publication, temperature not specified in the publication | Thermococcus kodakarensis | |
7.3 | - |
ADP | presence of Mg2+, pH and temperature not specified in the publication | Thermococcus kodakarensis | |
7.3 | - |
ADP | presence of Mg2+, pH not specified in the publication, temperature not specified in the publication | Thermococcus kodakarensis | |
12 | - |
2-deoxy-alpha-D-ribose 1-phosphate | presence of Mg2+, pH and temperature not specified in the publication | Thermococcus kodakarensis | |
12 | - |
2-deoxy-alpha-D-ribose-1-phosphate | presence of Mg2+, pH not specified in the publication, temperature not specified in the publication | Thermococcus kodakarensis | |
19 | - |
GDP | presence of Mg2+, pH and temperature not specified in the publication | Thermococcus kodakarensis | |
19 | - |
GDP | presence of Mg2+, pH not specified in the publication, temperature not specified in the publication | Thermococcus kodakarensis |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Ca2+ | divalent cation required, Mg2+ and Ca2+ are the most preferred. 107% of the activtiy with Mg2+ | Thermococcus kodakarensis | |
Co2+ | 59% of the activtiy with Mg2+ | Thermococcus kodakarensis | |
Mg2+ | divalent cation required, Mg2+ and Ca2+ are the most preferred | Thermococcus kodakarensis | |
additional information | activities with Mn2+, Ni2+, Zn2+ and Cu2+ are all less than 20% of that with Mg2+ | Thermococcus kodakarensis |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ADP + alpha-D-ribose-1-phosphate | Thermococcus kodakarensis | - |
AMP + alpha-D-ribose 1,5-bisphosphate | - |
? | |
alpha-D-ribose 1-phosphate + ADP | Thermococcus kodakarensis | - |
alpha-D-ribose 1,5-bisphosphate + AMP | - |
ir |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Thermococcus kodakarensis | Q5JDG9 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
2-deoxy-alpha-D-ribose 1-phosphate + ADP | - |
Thermococcus kodakarensis | 2-deoxy-alpha-D-ribose 1,5-bisphosphate + AMP | - |
ir | |
ADP + 2-deoxy-alpha-D-ribose-1-phosphate | - |
Thermococcus kodakarensis | AMP + 2-deoxy-alpha-D-ribose 1,5-bisphosphate | - |
? | |
ADP + alpha-D-ribose-1-phosphate | - |
Thermococcus kodakarensis | AMP + alpha-D-ribose 1,5-bisphosphate | - |
? | |
alpha-D-ribose 1-phosphate + ADP | - |
Thermococcus kodakarensis | alpha-D-ribose 1,5-bisphosphate + AMP | - |
ir | |
alpha-D-ribose 1-phosphate + ADP | irreversible under physiological conditions | Thermococcus kodakarensis | alpha-D-ribose 1,5-bisphosphate + AMP | irreversible under physiological conditions | ir | |
alpha-D-ribose 1-phosphate + GDP | irreversible under physiological conditions | Thermococcus kodakarensis | alpha-D-ribose 1,5-bisphosphate + GMP | - |
ir | |
GDP + alpha-D-ribose-1-phosphate | 56% of the activity with ADP | Thermococcus kodakarensis | GMP + alpha-D-ribose 1,5-bisphosphate | - |
? | |
additional information | no substrates: CDP, diphosphate | Thermococcus kodakarensis | ? | - |
? | |
UDP + alpha-D-ribose-1-phosphate | 9% of the activity with ADP | Thermococcus kodakarensis | UMP + alpha-D-ribose 1,5-bisphosphate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
ADP-dependent ribose-1-phosphate kinase | - |
Thermococcus kodakarensis |
TK2029 | - |
Thermococcus kodakarensis |
TK2029 | locus name | Thermococcus kodakarensis |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
85 | - |
- |
Thermococcus kodakarensis |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
73 | - |
2-deoxy-alpha-D-ribose 1-phosphate | presence of Mg2+, pH and temperature not specified in the publication | Thermococcus kodakarensis | |
73 | - |
2-deoxy-alpha-D-ribose-1-phosphate | presence of Mg2+, pH not specified in the publication, temperature not specified in the publication | Thermococcus kodakarensis | |
189 | - |
GDP | presence of Mg2+, pH and temperature not specified in the publication | Thermococcus kodakarensis | |
189 | - |
GDP | presence of Mg2+, pH not specified in the publication, temperature not specified in the publication | Thermococcus kodakarensis | |
485 | - |
alpha-D-ribose 1-phosphate | presence of Mg2+, pH and temperature not specified in the publication | Thermococcus kodakarensis | |
485 | - |
alpha-D-ribose-1-phosphate | presence of Mg2+, pH not specified in the publication, temperature not specified in the publication | Thermococcus kodakarensis | |
612 | - |
ADP | presence of Mg2+, pH and temperature not specified in the publication | Thermococcus kodakarensis | |
612 | - |
ADP | presence of Mg2+, pH not specified in the publication, temperature not specified in the publication | Thermococcus kodakarensis | |
856 | 1160 | ADP | depending on the presence of Ca2+, pH and temperature not specified in the publication | Thermococcus kodakarensis | |
856 | - |
ADP | presence of Ca2+, pH not specified in the publication, temperature not specified in the publication | Thermococcus kodakarensis |
pH Minimum | pH Maximum | Comment | Organism |
---|---|---|---|
5 | 8 | - |
Thermococcus kodakarensis |
kcat/KM Value [1/mMs-1] | kcat/KM Value Maximum [1/mMs-1] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
6.3 | - |
2-deoxy-alpha-D-ribose-1-phosphate | presence of Mg2+, pH not specified in the publication, temperature not specified in the publication | Thermococcus kodakarensis | |
10.2 | - |
GDP | presence of Mg2+, pH not specified in the publication, temperature not specified in the publication | Thermococcus kodakarensis | |
83.6 | - |
ADP | presence of Mg2+, pH not specified in the publication, temperature not specified in the publication | Thermococcus kodakarensis | |
204 | - |
ADP | presence of Ca2+, pH not specified in the publication, temperature not specified in the publication | Thermococcus kodakarensis | |
915 | - |
alpha-D-ribose-1-phosphate | presence of Mg2+, pH not specified in the publication, temperature not specified in the publication | Thermococcus kodakarensis |