Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 2.7.1.21 extracted from

  • Hussein, I.T.; Menashy, R.V.; Field, H.J.
    Penciclovir is a potent inhibitor of feline herpesvirus-1 with susceptibility determined at the level of virus-encoded thymidine kinase (2008), Antiviral Res., 78, 268-274.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
penciclovir three PCV-resistant FHV-1 variants selected in vitro carry mutations in the TK gene. Penciclovir is a potent selective inhibitor of Feline herpesvirus-1. The virus-encoded thymidine kinase is an important determinant of the virus susceptibility to nucleoside analogues Felid alphaherpesvirus 1

Organism

Organism UniProt Comment Textmining
Felid alphaherpesvirus 1
-
-
-