Cloned (Comment) | Organism |
---|---|
- |
Homo sapiens |
Protein Variants | Comment | Organism |
---|---|---|
V106M | results in tetrameric structure with high thymidine affinity | Homo sapiens |
General Stability | Organism |
---|---|
stable in the presence of ATP, bovine serum albumin and CHAPS | Homo sapiens |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0005 | - |
thymidine | pH 8 | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
25000 | - |
2 * 25000, rLyTK1Val-106 | Homo sapiens |
25000 | - |
4 * 25000, rLyTK1Met-106 | Homo sapiens |
50000 | - |
rLyTK1Val-106, gel filtration | Homo sapiens |
100000 | - |
rLyTK1Met-106, gel filtration | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Purification (Comment) | Organism |
---|---|
rLyTK1Val-106 and rLyTK1Met-106 | Homo sapiens |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
lymphocyte | healthy and leucemic cells | Homo sapiens | - |
Subunits | Comment | Organism |
---|---|---|
dimer | 2 * 25000, rLyTK1Val-106 | Homo sapiens |
tetramer | 4 * 25000, rLyTK1Met-106 | Homo sapiens |
Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
---|---|---|---|
15 | - |
rLyTK1Met-106: 50% loss of activity within 41 min, rLyTK1Val-106: 50% loss of activity after 392 min | Homo sapiens |
25 | - |
50% loss of activity within 4 min, rLyTK1Met-106 | Homo sapiens |