Literature summary for 2.7.1.202 extracted from

Lolkema, J.S.; ten Hoeve-Duurkens, R.H.; Robillard, G.T.
The phosphoenolpyruvate-dependent fructose-specific phosphotransferase system in Rhodopseudomonas sphaeroides. EIIFru possesses a Zn2+-binding site and a dithiol/disulfide redox centre (1986), Eur. J. Biochem., 154, 651-656.

Search for more literature for 2.7.1.202

Activating Compound

Activating Compound	Comment	Organism	Structure
Dithiol	essential for activity	Cereibacter sphaeroides

General Stability

General Stability	Organism
binding of zinc to or phosphorylating the enzyme protects it against trypsin inactivation	Cereibacter sphaeroides

Inhibitors

Inhibitors	Comment	Organism	Structure
ferricyanide	addition of 0.2 mM ferricyanide causes a rapid oxidation of the enzyme	Cereibacter sphaeroides
N-ethylmaleimide	-	Cereibacter sphaeroides
Trypsin	-	Cereibacter sphaeroides

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
membrane	-	Cereibacter sphaeroides	16020	-

Metals/Ions

Metals/Ions	Comment	Organism	Structure
additional information	metal ions are not required for the exchange activity of the enzyme	Cereibacter sphaeroides
Zn2+	contains zinc	Cereibacter sphaeroides

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
[protein]-Npi-phospho-L-histidine + D-fructose[side 1]	Cereibacter sphaeroides	-	[protein]-L-histidine + D-fructose 1-phosphate[side 2]	-	?

Organism

Organism	UniProt	Comment	Textmining
Cereibacter sphaeroides	-	-	-

Posttranslational Modification

Posttranslational Modification	Comment	Organism
phosphoprotein	-	Cereibacter sphaeroides

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
[protein]-Npi-phospho-L-histidine + D-fructose[side 1]	-	Cereibacter sphaeroides	[protein]-L-histidine + D-fructose 1-phosphate[side 2]	-	?

Synonyms

Synonyms	Comment	Organism
EIIFru	-	Cereibacter sphaeroides

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Release 2023.1 (January 2023)