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BRENDA support

Literature summary for 2.7.1.2 extracted from

  • Kumar, P.S.; Kumar, Y.N.; Prasad, U.V.; Yeswanth, S.; Swarupa, V.; Vasu, D.; Venkatesh, K.; Srikanth, L.; Rao, V.K.; Sarma, P.V.
    Comparative structural and functional analysis of Staphylococcus aureus glucokinase with other bacterial glucokinases (2014), Indian J. Pharm. Sci., 76, 430-436.
    View publication on PubMedView publication on EuropePMC

Crystallization (Commentary)

Crystallization (Comment) Organism
homology modeling of structure. Staphylococcus aureus glucokinase exhibits very close homology with Enterococcus faecalis and Clostridium difficle while with other bacteria it show a high degree of variations both in domain and nondomain regions. Glucose interacts with residues V77, N114, S161 and G160 forming a total of eight hydrogen bonds. Glucose docking score is -12.3697 kcal/mol Staphylococcus aureus

Organism

Organism UniProt Comment Textmining
Staphylococcus aureus H6UH58
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Staphylococcus aureus ATCC 12600 H6UH58
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