Literature summary for 2.7.1.199 extracted from

Oh, H.; Park, Y.; Park, C.
A mutated PtsG, the glucose transporter, allows uptake of D-ribose (1999), J. Biol. Chem., 274, 14006-14011.

Search for more literature for 2.7.1.199

Protein Variants

Protein Variants	Comment	Organism
F37Y	the mutant shows reduced activity with D-glucose and therefore increased activity towards D-ribose	Escherichia coli
G176D	the mutant shows reduced activity with D-glucose and therefore increased activity towards D-ribose	Escherichia coli
G281D	the mutant shows reduced activity with D-glucose and therefore increased activity towards D-ribose	Escherichia coli
I283T	the mutant shows reduced activity with D-glucose and therefore increased activity towards D-ribose	Escherichia coli
L289Q	the mutant shows reduced activity with D-glucose and therefore increased activity towards D-ribose	Escherichia coli

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
[protein]-Npi-phospho-L-histidine + D-glucose[side 1]	Escherichia coli	-	[protein]-L-histidine + D-glucose 6-phosphate[side 2]	-	?

Organism

Organism	UniProt	Comment	Textmining
Escherichia coli	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
additional information	the wild type enzyme does not transport D-ribose	Escherichia coli	?	-	?
[protein]-Npi-phospho-L-histidine + D-glucose[side 1]	-	Escherichia coli	[protein]-L-histidine + D-glucose 6-phosphate[side 2]	-	?

Synonyms

Synonyms	Comment	Organism
glucose-specific transporter of phosphoenolpyruvate:carbohydrate phosphotransferase system	-	Escherichia coli
IIBCGlc	-	Escherichia coli
PtsG	-	Escherichia coli

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Release 2023.1 (January 2023)