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Literature summary for 2.7.1.199 extracted from
- Characterization of the presumptive phosphorylation sites of the Bacillus subtilis glucose permease by site-directed mutagenesis: implication in glucose transport and catabolite repression (1997), FEMS Microbiol. Lett., 156, 233-238.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expressed in Escherichia coli HB101 cells | Bacillus subtilis |
Protein Variants
| Protein Variants | Comment | Organism |
|---|---|---|
| C461D | the mutant shows only weak repression of beta-xylosidase synthesis compared to the wild type enzyme | Bacillus subtilis |
| H620D | the mutant shows only weak repression of beta-xylosidase synthesis compared to the wild type enzyme | Bacillus subtilis |
| T324I | the mutant shows only weak repression of beta-xylosidase synthesis compared to the wild type enzyme | Bacillus subtilis |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| [protein]-Npi-phospho-L-histidine + D-glucose[side 1] | Bacillus subtilis | - |
[protein]-L-histidine + D-glucose 6-phosphate[side 2] | - |
? |  |
| [protein]-Npi-phospho-L-histidine + D-glucose[side 1] | Bacillus subtilis 168 | - |
[protein]-L-histidine + D-glucose 6-phosphate[side 2] | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Bacillus subtilis | - |
- |
- |
| Bacillus subtilis 168 | - |
- |
- |
Posttranslational Modification
| Posttranslational Modification | Comment | Organism |
|---|---|---|
| phosphoprotein | phosphorylation of both domains IIAGlc and IIBGlc is required for efficient glucose transport | Bacillus subtilis |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| [protein]-Npi-phospho-L-histidine + D-glucose[side 1] | - |
Bacillus subtilis | [protein]-L-histidine + D-glucose 6-phosphate[side 2] | - |
? | |
| [protein]-Npi-phospho-L-histidine + D-glucose[side 1] | - |
Bacillus subtilis 168 | [protein]-L-histidine + D-glucose 6-phosphate[side 2] | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| glucose permease | - |
Bacillus subtilis |
| IIAGlc | enzyme domain | Bacillus subtilis |
| IIBGlc | enzyme domain | Bacillus subtilis |
| PtsG | - |
Bacillus subtilis |
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