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Literature summary for 2.7.1.187 extracted from
- Acarbose 7-phosphotransferase from Actinoplanes sp.: purification, properties, and possible physiological function (1996), J. Antibiot., 49, 664-668.
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.47 | - |
ATP | pH 7.8, 30°C | Actinoplanes sp. |  |
| 0.81 | - |
acarbose | pH 7.8, 30°C | Actinoplanes sp. | |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 36200 | - |
gel filtration | Actinoplanes sp. |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + acarbose | Actinoplanes sp. | - |
ADP + acarbose 7'''-phosphate | - |
? | |
| ATP + acarbose | Actinoplanes sp. SN 223/29 | - |
ADP + acarbose 7'''-phosphate | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Actinoplanes sp. | - |
- |
- |
| Actinoplanes sp. SN 223/29 | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Actinoplanes sp. |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + acarbose | - |
Actinoplanes sp. | ADP + acarbose 7'''-phosphate | - |
? | |
| ATP + acarbose | high specificity for acarbose and some related compounds containing the pseudodisaccharide moiety. No activity with glucose, maltose, maltotriose, maltotetraose, streptomycin, kanamycin, neomycin | Actinoplanes sp. | ADP + acarbose 7'''-phosphate | - |
? | |
| ATP + acarbose | - |
Actinoplanes sp. SN 223/29 | ADP + acarbose 7'''-phosphate | - |
? | |
| ATP + acarbose | high specificity for acarbose and some related compounds containing the pseudodisaccharide moiety. No activity with glucose, maltose, maltotriose, maltotetraose, streptomycin, kanamycin, neomycin | Actinoplanes sp. SN 223/29 | ADP + acarbose 7'''-phosphate | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| acarbose 7-kinase | - |
Actinoplanes sp. |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 30 | - |
assay at | Actinoplanes sp. |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 7.8 | - |
assay at | Actinoplanes sp. |
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