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Literature summary for 2.7.1.182 extracted from

  • Almeida, J.; Azevedo, M.d.a..S.; Spicher, L.; Glauser, G.; vom Dorp, K.; Guyer, L.; del Valle Carranza, A.; Asis, R.; de Souza, A.P.; Buckeridge, M.; Demarco, D.; Bres, C.; Rothan, C.; Peres, L.E.; Hoertensteiner, S.; Kessler, F.; Doermann, P.; Carrari, F.; Rossi, M.
    Down-regulation of tomato phytol kinase strongly impairs tocopherol biosynthesis and affects prenyllipid metabolism in an organ-specific manner (2016), J. Exp. Bot., 67, 919-934.
    View publication on PubMedView publication on EuropePMC
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Cloned(Commentary)

Cloned (Comment) Organism
gene VTE5, genotyping, identification of enzyme-deficient mutants, phylogenetic analysis Solanum lycopersicum

Protein Variants

Protein Variants Comment Organism
additional information generation of SlVTE5-RNAi transgenic lines, RNAi-mediated silencing of the Solyc03g071720 locus using primers RNAi-VTE5-F and RNAi-VTE5-R. TILLING-based molecular screening is used to identify a loss-offunction mutation in SlFOLK using an EMS-mutagenized tomato collection Solanum lycopersicum

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
CTP + phytol Solanum lycopersicum
-
 CDP + phytyl phosphate
-
 ?

Organism

Organism UniProt Comment Textmining
Solanum lycopersicum A0A3Q7FJ72 cv. Micro-Tom
-

Source Tissue

Source Tissue Comment Organism Textmining
fruit mature green and ripe Solanum lycopersicum
-
leaf
-
 Solanum lycopersicum
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
CTP + phytol
-
 Solanum lycopersicum CDP + phytyl phosphate
-
 ?

Synonyms

Synonyms Comment Organism
phytol kinase
-
 Solanum lycopersicum
SlVTE5
-
 Solanum lycopersicum
VTE5
-
 Solanum lycopersicum

Cofactor

Cofactor Comment Organism Structure
CTP
-
 Solanum lycopersicum

General Information

General Information Comment Organism
malfunction downregulation of tomato phytol kinase strongly impairs tocopherol biosynthesis and affects prenyllipid metabolism in an organ-specific manner. VTE5-deficient plants display starch accumulation and lower CO2 assimilation in leaves associated with mild yield penalty. Carbohydrate export blockage in the VTE5-deficient plants affecting tomato fruit quality. Chlorophyll content is not affected in SlVTE5-RNAi lines. Phenotype, overview Solanum lycopersicum
metabolism the enzyme is essential in tocopherol biosynthesis, tocopherol biosynthetic and related pathways, overview Solanum lycopersicum
physiological function chlorophyll phytol tail recycling depends on phytol kinase activity. Phytol diphosphate is required for synthesis of tocopherol involving the condensation with an aromatic head group Solanum lycopersicum