Literature summary for 2.7.1.171 extracted from

Conner, J.R.; Beisswenger, P.J.; Szwergold, B.S.
The expression of the genes for fructosamine-3-kinase and fructosamine-3-kinase-related protein appears to be constitutive and unaffected by environmental signals (2004), Biochem. Biophys. Res. Commun., 323, 932-936.

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Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
fibroblast	cultured fibroblasts treated with conditions mimicking the hormonal and biochemical profile of the diabetic state show no changes in fructosamine-3-kinase expression relative to untreated cells. FN3K acts as protein repair enzyme and is expressed constitutively in human cells independently of some of the variables altered in the diabetic state	Homo sapiens	-
kidney	highest levels of FN3K expression are found in tissues known to be susceptible to glycation and diabetic complications such as kidney and neurons	Homo sapiens	-
neuron	highest levels of FN3K expression are found in tissues known to be susceptible to glycation and diabetic complications such as kidney and neurons	Homo sapiens	-

Synonyms

Synonyms	Comment	Organism
fructosamine-3-kinase	-	Homo sapiens

Expression

Organism	Comment	Expression
Homo sapiens	highest levels of FN3K expression are found in tissues known to be susceptible to glycation and diabetic complications such as kidney and neurons. Cultured fibroblasts treated with conditions mimicking the hormonal and biochemical profile of the diabetic state show no changes in fructosamine-3-kinase expression relative to untreated cells. FN3K acts as protein repair enzyme and is expressed constitutively in human cells independently of some of the variables altered in the diabetic state	additional information

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Release 2023.1 (January 2023)