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Literature summary for 2.7.1.17 extracted from

  • Khattab, S.; Kodaki, T.
    Efficient bioethanol production by overexpression of endogenous Saccharomyces cerevisiae xylulokinase and NADPH-dependent aldose reductase with mutated strictly NADP+-dependent Pichia stipitis xylitol dehydrogenase (2014), Process Biochem., 49, 1838-1842.
No PubMed abstract available

Application

Application Comment Organism
synthesis construction of a Saccharomyces cerevisiae strain overexpressing GRE3-encoded NADPH-dependent aldose reductase and xylulokinase with a mutated strictly NADP+-dependent Pichia stipitis xylitol dehydrogenase. The recombinant strain efficiently ferments xylose and glucose mixture and the ethanol production is 21.4% higher than that of an isogenic constructed reference strain expressing Pichia stipitis xylose reductase. The yield of ethanol production increases from 0.395 g ethanol/g sugar to 0.435 g ethanol/g sugar after glucose depletion. Xylitol accumulation (0.6% of total sugar) is considerably lower than that of the reference strain (4.8% of total sugar) Saccharomyces cerevisiae

Cloned(Commentary)

Cloned (Comment) Organism
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Saccharomyces cerevisiae

Organism

Organism UniProt Comment Textmining
Saccharomyces cerevisiae
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