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Literature summary for 2.7.1.16 extracted from

  • Kawaguchi, H.; Sasaki, M.; Vertes, A.A.; Inui, M.; Yukawa, H.
    Engineering of an L-arabinose metabolic pathway in Corynebacterium glutamicum (2008), Appl. Microbiol. Biotechnol., 77, 1053-1062.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
expression in Corynebacterium glutamicum. Corynebacterium glutamicum is metabolically engineered to broaden its substrate utilization range to include L-arabinose. The resultant CRA1 recombinant strain expressed the Escherichia coli genes araA, araB, and araD encoding L-arabinose isomerase, L-ribulokinase, and L-ribulose-5-phosphate 4-epimerase, respectively, under the control of a constitutive promoter. Unlike the wild-type strain, CRA1 is able to grow on mineral salts medium containing L-arabinose as the sole carbon and energy source. The three cloned genes are expressed to the same levels whether cells are cultured in the presence of D-glucose or L-arabinose. Strain CRA1 is able to utilize L-arabinose as a substrate for organic acid production even in the presence of D-glucose Escherichia coli

Organism

Organism UniProt Comment Textmining
Escherichia coli
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-
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Synonyms

Synonyms Comment Organism
AraB
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Escherichia coli