Cloned (Comment) | Organism |
---|---|
gene itpk, quantitative RT-PCR enzyme expression analysis | Gloiopeltis furcata |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + 1D-myo-inositol 1,3,4-trisphosphate | Gloiopeltis furcata | - |
ADP + 1D-myo-inositol 1,3,4,5-tetrakisphosphate | - |
? | |
ATP + 1D-myo-inositol 1,3,4-trisphosphate | Gloiopeltis furcata | - |
ADP + 1D-myo-inositol 1,3,4,6-tetrakisphosphate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Gloiopeltis furcata | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
additional information | expression pattern of gene ITPK as a drought-related hub gene | Gloiopeltis furcata | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + 1D-myo-inositol 1,3,4-trisphosphate | - |
Gloiopeltis furcata | ADP + 1D-myo-inositol 1,3,4,5-tetrakisphosphate | - |
? | |
ATP + 1D-myo-inositol 1,3,4-trisphosphate | - |
Gloiopeltis furcata | ADP + 1D-myo-inositol 1,3,4,6-tetrakisphosphate | - |
? | |
ATP + 1D-myo-inositol 3,4,5,6-tetrakisphosphate | - |
Gloiopeltis furcata | ADP + 1D-myo-inositol 1,3,4,5,6-pentakisphosphate | - |
r | |
additional information | ITPK can also interconvert Ins (3,4,5,6)P4 and Ins (1,3,4,5,6)P5 within a substrate cycle to regulate the concentration of Ins (3,4,5,6)P4 | Gloiopeltis furcata | ? | - |
- |
Synonyms | Comment | Organism |
---|---|---|
ITPK | - |
Gloiopeltis furcata |
Organism | Comment | Expression |
---|---|---|
Gloiopeltis furcata | successive dehydration treatment induces the enzyme expression in red sea weed | up |
General Information | Comment | Organism |
---|---|---|
metabolism | pathways enriched analysis indicates that the ubiquitin-mediated proteolysis pathway (UPP) and phosphatidylinositol (PI) signaling system are crucial for a successful transcriptional response in Gloiopeltis furcata to simulated natural tidal changes with twoconsecutive dehydration-rehydration cycles, overview. Genes encoding ubiquitin-protein ligase E3 (E3-1), SUMO-activating enzyme sub-unit 2 (SAE2), calmodulin (CaM), and inositol-1,3,4-trisphosphate 5/6-kinase (ITPK) are the hub genes which respond positively to two successive dehydration treatments. Network-based interactions with hub genes indicate that transcription factor (e.g. TFIID), RNA modification (e.g. DEAH) and osmotic adjustment (e.g. MIP, ABC1, Bam1) are related to these two pathways. The PI signal connected with Ca2+/CaM pathway responds to dehydration, and the role of CaM and ITPK in signal transduction | Gloiopeltis furcata |
physiological function | enzyme ITPK is the key regulatory enzyme at the branch point for the synthesis of InsP4 isomers [e.g. Ins(1,3,4,5)P4, Ins(1,3,4,6)P4 and Ins(3,4,5,6)P4], inositol pentakisphosphate (InsP5) and inositol hexaphosphate (InsP6). Ins (3,4,5,6)P4 can act as second messenger and play important roles in signal transduction | Gloiopeltis furcata |