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Literature summary for 2.7.1.158 extracted from

  • Basak, N.; Krishnan, V.; Pandey, V.; Punjabi, M.; Hada, A.; Marathe, A.; Jolly, M.; Palaka, B.K.; Ampasala, D.R.; Sachdev, A.
    Expression profiling and in silico homology modeling of inositol pentakisphosphate 2-kinase, a potential candidate gene for low phytate trait in soybean (2020), 3 Biotech, 10, 268 .
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.7.1.158

Cloned(Commentary)

Cloned (Comment) Organism
gene Glyma04g03240, sequence comaprisons and phylogenetic tree, quantitative real-time expression analysis Glycine max
gene Glyma06g03310, sequence comaprisons and phylogenetic tree, quantitative real-time expression analysis Glycine max
gene GmIpk1, sequence comparisons and phylogenetic tree, quantitative real-time expression analysis Glycine max

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+ required Glycine max

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + 1D-myo-inositol 1,3,4,5,6-pentakisphosphate Glycine max
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 ADP + 1D-myo-inositol hexakisphosphate
-
 ?

Organism

Organism UniProt Comment Textmining
Glycine max I1JT87 var. Pusa 9712
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Glycine max U5TRK1 var. Pusa 9712
-

Source Tissue

Source Tissue Comment Organism Textmining
flower low expression Glycine max
-
flower moderate expression Glycine max
-
flower very low expression Glycine max
-
leaf very low expression Glycine max
-
leaf low to moderate expression Glycine max
-
root very low expression Glycine max
-
seed developing, low expression Glycine max
-
seed developing, very high expression Glycine max
-
stem moderate expression Glycine max
-
stem very low expression Glycine max
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + 1D-myo-inositol 1,3,4,5,6-pentakisphosphate
-
 Glycine max ADP + 1D-myo-inositol hexakisphosphate
-
 ?
additional information binding sites of ADP and IP6 are observed to be present side by side with few common interacting amino acid residues: R193, K171. The residues that are making interactions with ADP include W130, K171, R193, H197, K201, Q204, and N239, whereas the residues that are making interactions with IP6 include G17, E18, G19, A20, N22, L23, V24, R40, K43, R131, R169, K171, R193, R242, and S373 Glycine max ?
-
-

Subunits

Subunits Comment Organism
More secondary structure prediction revealing that 74.46% of amino acids are in alpha-helix, whereas 57.64% of residues in beta-sheets and 12.19% in coil conformations, structure modeling, overview Glycine max

Synonyms

Synonyms Comment Organism
Glyma04g03240
-
 Glycine max
Glyma06g03310
-
 Glycine max
GmIpk1
-
 Glycine max
inositol pentakisphosphate 2-kinase
-
 Glycine max
Ipk1
-
 Glycine max

Cofactor

Cofactor Comment Organism Structure
ATP
-
 Glycine max

General Information

General Information Comment Organism
evolution differential spatial and temporal expression profiling of gene GmIpk1 and its two homologues Glyma06g03310 and Glyma04g03310 in Glycine max Glycine max
metabolism inositol 1,3,4,5,6-pentakisphosphate 2-kinase catalyzes the terminal step in the phytic acid biosynthetic pathway Glycine max
metabolism nositol 1,3,4,5,6-pentakisphosphate 2-kinase catalyzes the terminal step in the phytic acid biosynthetic pathway Glycine max
additional information molecular docking study Glycine max
additional information three-dimensional homolgy modelling, GmIPK1 protein model (PMD ID PM0079931), using Arabidopsis thaliana enzyme structure (PDB ID 4AQK) as template, structure-function relationship of GmIPK1, molecular dynamics simulations and molecular docking study, overview Glycine max
physiological function GmIPK1 plays a significant role in phytate synthesis Glycine max