Application | Comment | Organism |
---|---|---|
pharmacology | the PI3Kgamma signaling pathway may represent a suitable target for the development of therapeutic strategies for human diseases characterized by vascular leakage | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Mus musculus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
retina | - |
Mus musculus | - |
retina | - |
Homo sapiens | - |
Synonyms | Comment | Organism |
---|---|---|
CXCR2/phosphatidylinositol 3-kinase gamma | - |
Mus musculus |
CXCR2/phosphatidylinositol 3-kinase gamma | - |
Homo sapiens |
General Information | Comment | Organism |
---|---|---|
physiological function | isozyme PI3Kgamma is involved in inteleukin-8-induced increase of endothelial monolayer permeability and is able to limit neovascularization and choroidal edema, as well as macrophage infiltration, therefore contributes to reduce laser-induced retinal damage | Mus musculus |
physiological function | isozyme PI3Kgamma is involved in inteleukin-8-induced increase of endothelial monolayer permeability and is able to limit neovascularization and choroidal edema, as well as macrophage infiltration, therefore contributes to reduce laser-induced retinal damage | Homo sapiens |