Literature summary for 2.7.1.153 extracted from

Brock, C.; Schaefer, M.; Reusch, H.P.; Czupalla, C.; Michalke, M.; Spicher, K.; Schultz, G.; Nurnberg, B.
Roles of Gbg in membrane recruitment and activation of p110gamma/p101 phosphoinositide 3-kinase gamma (2003), J. Cell Biol., 160, 89-99.

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Activating Compound

Activating Compound	Comment	Organism	Structure
G-protein beta,gamma	in vivo, activation of enzyme by a mechanism assigning specific roles for both enzyme subunits, membrane recruitment via the noncatalytic p101 subunit, and direct stimulation of p110gamma	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	P48736	GFP-tag, expression in HEK cell	-

Subunits

Subunits	Comment	Organism
More	G-protein beta,gamma recruits the enzyme from the cytosol to the mebrane by interaction with ist p101 subunit	Homo sapiens

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Release 2023.1 (January 2023)