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Literature summary for 2.7.1.151 extracted from

  • Saiardi, A.; Resnick, A.C.; Snowman, A.M.; Wendland, B.; Snyder, S.H.
    Inositol pyrophosphates regulate cell death and telomere length through phosphoinositide 3-kinase-related protein kinases (2005), Proc. Natl. Acad. Sci. USA, 102, 1911-1914.
    View publication on PubMedView publication on EuropePMC
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Protein Variants

Protein Variants Comment Organism
additional information an enzyme-deficient mutant strain is resistant to inhibition by wortmannin, while transformation with the wild-type enzyme reverses the effect, the enzyme-deficient mutant shows increased phosphatidylinositol 4,5-bisphosphate levels Saccharomyces cerevisiae

Inhibitors

Inhibitors Comment Organism Structure
additional information an enzyme-deficient mutant strain is resistant to inhibition by wortmannin, while transformation with the wild-type enzyme reverses the effect Saccharomyces cerevisiae
Wortmannin
-
 Saccharomyces cerevisiae

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Saccharomyces cerevisiae the enzyme is involved in regulation of telomere length and cell death, overview ?
-
 ?

Organism

Organism UniProt Comment Textmining
Saccharomyces cerevisiae
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information the enzyme is involved in regulation of telomere length and cell death, overview Saccharomyces cerevisiae ?
-
 ?

Synonyms

Synonyms Comment Organism
Arg82
-
 Saccharomyces cerevisiae
Impk
-
 Saccharomyces cerevisiae
inositol polyphosphate multikinase
-
 Saccharomyces cerevisiae