Literature summary for 2.7.1.150 extracted from

Rusten, T.E.; Rodahl, L.M.; Pattni, K.; Englund, C.; Samakovlis, C.; Dove, S.; Brech, A.; Stenmark, H.
Fab1 phosphatidylinositol 3-phosphate 5-kinase controls trafficking but not silencing of endocytosed receptors (2006), Mol. Biol. Cell, 17, 3989-4001.

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Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
ATP + 1-phosphatidyl-1D-myo-inositol 3-phosphate	Drosophila sp. (in: flies)	Fab1 phosphatidylinositol 3-phosphate 5-kinase controls trafficking but not silencing of endocytosed receptors. Drosophila fab1 mutants contain undetectable phosphatidylinositol 3,5-bisphosphate levels, show profound increases in cell and organ size, and die at the pupal stage	ADP + 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate	-	?

Organism

Organism	UniProt	Comment	Textmining
Drosophila sp. (in: flies)	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
ATP + 1-phosphatidyl-1D-myo-inositol 3-phosphate	Fab1 phosphatidylinositol 3-phosphate 5-kinase controls trafficking but not silencing of endocytosed receptors. Drosophila fab1 mutants contain undetectable phosphatidylinositol 3,5-bisphosphate levels, show profound increases in cell and organ size, and die at the pupal stage	Drosophila sp. (in: flies)	ADP + 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate	-	?

Synonyms

Synonyms	Comment	Organism
Fab1 phosphatidylinositol 3-phosphate 5-kinase	-	Drosophila sp. (in: flies)
Fab1/PIKfyve	-	Drosophila sp. (in: flies)
PtdIns(3)P 5-kinase	-	Drosophila sp. (in: flies)

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Release 2023.1 (January 2023)