Protein Variants | Comment | Organism |
---|---|---|
additional information | generation of an Arabidopsis thaliana cell-death mutant, accelerated cell death5 (acd5), which accumulates ceramides and exhibits spontaneous cell death late in development. NaCl enhances disease resistance and suppresses cell death in ceramide kinase mutants. The effect of NaCl is partly dependent on the antagonistic interaction between endogenous abscisic acid (ABA) and salicylic acid (SA). The intact ABA pathway may not be required for this effect. The response of the acd5 mutant to abiotic stress shows that the mutants do not have the cell-death phenotype. 300 mM NaCl suppresses the cell-death phenotype of the acd5 mutant without inhibiting plant growth. NaCl treatment inhibits sphingolipid accumulation in the acd5 mutant and alters the endogenous levels of SA and ABA | Arabidopsis thaliana |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mg2+ | required | Arabidopsis thaliana |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + ceramide | Arabidopsis thaliana | - |
ADP + ceramide 1-phosphate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Arabidopsis thaliana | Q6USK2 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + ceramide | - |
Arabidopsis thaliana | ADP + ceramide 1-phosphate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
CERK | - |
Arabidopsis thaliana |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
ATP | - |
Arabidopsis thaliana |
General Information | Comment | Organism |
---|---|---|
malfunction | Arabidopsis thaliana cell-death mutant, accelerated cell death5 (acd5), which accumulates ceramides and exhibits spontaneous cell death late in development. NaCl enhances disease resistance and suppresses cell death in ceramide kinase mutants partly via a mechanism that depends on abscisic acid (ABA) and salicylic acid (SA) antagonistic interaction, and enhances disease resistance independent of pattern-triggered immune responses. 300 mM NaCl suppresses the cell-death phenotype of the acd5 mutant without inhibiting plant growth | Arabidopsis thaliana |