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Literature summary for 2.7.1.138 extracted from

  • Wijesinghe, D.S.; Lamour, N.F.; Gomez-Munoz, A.; Chalfant, C.E.
    Ceramide kinase and ceramide-1-phosphate (2007), Methods Enzymol., 434, 265-292.
    View publication on PubMed
Search for more literature for 2.7.1.138

Cloned(Commentary)

Cloned (Comment) Organism
expression in baculovirus-infected SF9 insect cells Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ceramide + ATP Homo sapiens CERK and C1P are playing significant biological roles in cell-signaling cascades ceramide 1-phosphate + ADP
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Purification (Commentary)

Purification (Comment) Organism
Ni-NTA affinity column chromatography Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
A-549 cell ceramide kinase amplified from an A549 cDNA library Homo sapiens
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
alpha-OH-C24:0 phytoceramide + ATP
-
 Homo sapiens alpha-OH-C24:0 phytoceramide 1-phosphate + ADP
-
 ?
alpha-OH-D-erythro-C6:0 ceramide + ATP
-
 Homo sapiens alpha-OH-D-erythro-C6:0 ceramide 1-phosphate + ADP
-
 ?
C26:0 phytoceramide + ATP
-
 Homo sapiens C26:0 phytoceramide 1-phosphate + ADP
-
 ?
ceramide + ATP
-
 Homo sapiens ceramide 1-phosphate + ADP
-
 ?
ceramide + ATP CERK and C1P are playing significant biological roles in cell-signaling cascades Homo sapiens ceramide 1-phosphate + ADP
-
 ?
D-erythro-C12:0 ceramide + ATP
-
 Homo sapiens D-erythro-C12:0 ceramide 1-phosphate + ADP
-
 ?
D-erythro-C14:0 ceramide + ATP
-
 Homo sapiens D-erythro-C14:0 ceramide 1-phosphate + ADP
-
 ?
D-erythro-C16:0 ceramide + ATP used for kinetic analysis of ceramide kinase activity Homo sapiens D-erythro-C16:0 ceramide 1-phosphate + ADP
-
 ?
D-erythro-C2:0 ceramide + ATP
-
 Homo sapiens D-erythro-C2:0 ceramide 1-phosphate + ADP
-
 ?
D-erythro-C2:0 dihydroceramide + ATP
-
 Homo sapiens D-erythro-C2:0 dihydroceramide 1-phosphate + ADP
-
 ?
D-erythro-C6:0 ceramide + ATP
-
 Homo sapiens D-erythro-C6:0 ceramide 1-phosphate + ADP
-
 ?
D-erythro-C6:0 dihydroceramide + ATP
-
 Homo sapiens D-erythro-C6:0 dihydroceramide 1-phosphate + ADP
-
 ?

Synonyms

Synonyms Comment Organism
CERK
-
 Homo sapiens