Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
endosome membrane | - |
Homo sapiens | 10008 | - |
Golgi apparatus | - |
Homo sapiens | 5794 | - |
membrane | - |
Homo sapiens | 16020 | - |
mitochondrial outer membrane | - |
Homo sapiens | 5741 | - |
mitochondrion | - |
Homo sapiens | 5739 | - |
trans-Golgi network | - |
Homo sapiens | 5802 | - |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Ca2+ | - |
Homo sapiens |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
62000 | - |
SDS-PAGE | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ceramide + ATP | Homo sapiens | ceramide kinase is a critical mediator of eicosanoid synthesis, and its product, ceramide 1-phosphate, is required for the production of prostaglandins in response to several inflammatory agonists, CERK requires ceramide actively transported to the trans-Golgi network via ceramide transport protein CERT | ceramide 1-phosphate + ADP | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
A-549 cell | - |
Homo sapiens | - |
HeLa cell | - |
Homo sapiens | - |
lung adenocarcinoma cell | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + ceramide | - |
Homo sapiens | ADP + ceramide 1-phosphate | - |
? | |
ATP + D-eythro-C16:0 ceramide | - |
Homo sapiens | ADP + D-eythro-C16:0 ceramide 1-phosphate | - |
? | |
ATP + D-eythro-C18:0 ceramide | - |
Homo sapiens | ADP + D-eythro-C18:0 ceramide 1-phosphate | - |
? | |
ATP + D-eythro-C20:0 ceramide | - |
Homo sapiens | ADP + D-eythro-C20:0 ceramide 1-phosphate | - |
? | |
ceramide + ATP | - |
Homo sapiens | ceramide 1-phosphate + ADP | - |
? | |
ceramide + ATP | ceramide kinase is a critical mediator of eicosanoid synthesis, and its product, ceramide 1-phosphate, is required for the production of prostaglandins in response to several inflammatory agonists, CERK requires ceramide actively transported to the trans-Golgi network via ceramide transport protein CERT | Homo sapiens | ceramide 1-phosphate + ADP | - |
? |
Synonyms | Comment | Organism |
---|---|---|
CERK | - |
Homo sapiens |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
ATP | - |
Homo sapiens |