Activating Compound | Comment | Organism | Structure |
---|---|---|---|
nerve growth factor | activates the PI3-K/Akt signaling pathway | Rattus norvegicus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
male SpragueDawley rats | - |
Posttranslational Modification | Comment | Organism |
---|---|---|
phosphoprotein | PI3-K is activated by phosphorylation through serine/threonine protein kinases | Rattus norvegicus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
hippocampus | - |
Rattus norvegicus | - |
neuron | - |
Rattus norvegicus | - |
Synonyms | Comment | Organism |
---|---|---|
PI3-K | - |
Rattus norvegicus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
ATP | - |
Rattus norvegicus |
General Information | Comment | Organism |
---|---|---|
metabolism | the PI3-K/Akt pathway plays a pivotal role in controlling the survival of neurons, although this activity declines during the aging process. NGF receptors and the PI3-K signaling pathway strongly influence cell survival | Rattus norvegicus |
physiological function | the PI3-K/Akt pathway plays a pivotal role in controlling the survival of neurons, although this activity declines during the aging process. NGF receptors and the PI3-K signaling pathway strongly influence cell survival | Rattus norvegicus |