Literature summary for 2.7.1.137 extracted from

Domin, J.; Pages, F.; Volinia, S.; Rittenhouse, S.E.; Zvelebil, M.J.; Stein, R.C.; Waterfield, M.D.
Cloning of a human phosphoinositide 3-kinase with a C2 domain that displays reduced sensitivity to the inhibitor wortmannin (1997), Biochem. J., 326, 139-147.

No PubMed abstract available

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Cloned(Commentary)

Cloned (Comment)	Organism
cloning of a human phosphoinositide 3-kinase with a C2 domain that displays reduced sensitivity to the inhibitor wortmannin	Homo sapiens

Inhibitors

Inhibitors	Comment	Organism	Structure
Wortmannin	phosphoinositide 3-kinase with a C2 domain displays reduced sensitivity to the inhibitor wortmannin	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
ATP + 1-phosphatidylinositol	-	Homo sapiens	ADP + phosphatidylinositol 3-phosphate	-	?
ATP + 1-phosphatidylinositol	-	Homo sapiens PI3K-C2alpha	ADP + phosphatidylinositol 3-phosphate	-	?

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Release 2023.1 (January 2023)