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Literature summary for 2.7.1.137 extracted from

  • Asano, T.; Kanda, A.; Katagiri, H.; Nawano, M.; Ogihara, T.; Inukai, K.; Anai, M.; Fukushima, Y.; Yazaki, Y.; Kikuchi, M.; Hooshmand-Rad, R.; Heldin, C.H.; Oka, Y.; Funaki, M.
    p110b is up-regulated during differentiation of 3T3-L1 cells and contributes to the highly insulin-responsive glucose transport activity (2000), J. Biol. Chem., 275, 17671-17676.
    View publication on PubMed
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Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Rattus norvegicus isoform p110b of the catalytic subunit plays a crucial role in cellular activities evoked acutely by insulin ?
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 ?

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
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-
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Source Tissue

Source Tissue Comment Organism Textmining
adipocyte 3T3-L1 Rattus norvegicus
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adipocyte during differentiation of 3T3-L1 cells into adipocytes, isoform p110b is up-regulated approximately 10-fold, expression of p110a is unaltered Rattus norvegicus
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + 1-phosphatidylinositol
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 Rattus norvegicus ADP + phosphatidylinositol 3-phosphate
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 ?
additional information isoform p110b of the catalytic subunit plays a crucial role in cellular activities evoked acutely by insulin Rattus norvegicus ?
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 ?

Subunits

Subunits Comment Organism
More isoforms of the p110 catalytic subunit: p110a or p110b Rattus norvegicus

Synonyms

Synonyms Comment Organism
p85/p110 type phosphatidylinositol kinase
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 Rattus norvegicus