Cloned (Comment) | Organism |
---|---|
gene Itpkc, quantitative real-time PCR expression analysis, recombinant expression in human HEK-293 cells | Mus musculus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
brush border | - |
Mus musculus | 5903 | - |
flagellum | - |
Mus musculus | - |
- |
microvillus | - |
Mus musculus | 5902 | - |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
90000 | - |
x * 90000, about, SDS-PAGE | Mus musculus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + 1D-myo-inositol 1,4,5-trisphosphate | Mus musculus | - |
ADP + 1D-myo-inositol 1,3,4,5-tetrakisphosphate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | Q7TS72 | gene Itpkc | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
brain | - |
Mus musculus | - |
caecum | - |
Mus musculus | - |
ependymal cell | - |
Mus musculus | - |
epididymis | low expression level | Mus musculus | - |
epithelium | tracheal and bronchial, multiciliated tracheal epithelial cells | Mus musculus | - |
kidney | - |
Mus musculus | - |
large intestine | high expression level | Mus musculus | - |
liver | - |
Mus musculus | - |
lung | - |
Mus musculus | - |
additional information | enzyme tissue expression analysis by immunohistochemic analysis and situ hybridization. Cells positive for ITPKC express either a multicilium (tracheal and bronchial epithelia, brain ependymal cells), microvilli forming a brush border (small and large intestine, and kidney proximal tubule cells) or a flagellum (spermatozoa) | Mus musculus | - |
proximal tubule | - |
Mus musculus | - |
salivary gland | - |
Mus musculus | - |
small intestine | - |
Mus musculus | - |
sperm cell | - |
Mus musculus | - |
spermatozoon | epididymal spermatozoa | Mus musculus | - |
spleen | - |
Mus musculus | - |
stomach | - |
Mus musculus | - |
testis | high expression level | Mus musculus | - |
thymus | - |
Mus musculus | - |
trachea | low expression level | Mus musculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + 1D-myo-inositol 1,4,5-trisphosphate | - |
Mus musculus | ADP + 1D-myo-inositol 1,3,4,5-tetrakisphosphate | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 90000, about, SDS-PAGE | Mus musculus |
Synonyms | Comment | Organism |
---|---|---|
inositol 1,4,5-trisphosphate 3-kinase C | - |
Mus musculus |
Itpkc | - |
Mus musculus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
ATP | - |
Mus musculus |
General Information | Comment | Organism |
---|---|---|
evolution | a member of the inositol 1,4,5-trisphosphate 3-kinases family | Mus musculus |
physiological function | role for ITPKC either in the development or the function of these specialized cellular structures | Mus musculus |