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Literature summary for 2.7.1.12 extracted from

  • Coffee, C.J.; Hu, A.S.L.
    The kinetic characterization of gluconokinase from a pseudomonad (1972), Arch. Biochem. Biophys., 149, 549-559.
    View publication on PubMed
Search for more literature for 2.7.1.12

Inhibitors

Inhibitors Comment Organism Structure
dADP weak Pseudomonas sp.
IDP weak Pseudomonas sp.

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.116
-
 ATP 30°C, pH 7.5 Pseudomonas sp.
1.04
-
 ATP 30°C, pH 7.5 Pseudomonas sp.

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+ required, maximal activation at a Mg2+ : ATP ratio of 1.0-2.0 Pseudomonas sp.
Mn2+ 60% as effective as Mg2+ in activation Pseudomonas sp.

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + D-gluconate Pseudomonas sp.
-
 ADP + 6-phospho-D-gluconate
-
 ?

Organism

Organism UniProt Comment Textmining
Pseudomonas sp.
-
-
-

Reaction

Reaction Comment Organism Reaction ID
ATP + D-gluconate = ADP + 6-phospho-D-gluconate sequential probably random mechanism Pseudomonas sp.
a

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + D-gluconate
-
 Pseudomonas sp. ADP + 6-phospho-D-gluconate
-
 ?
ATP + D-gluconate strict specificity for D-gluconate Pseudomonas sp. ADP + 6-phospho-D-gluconate
-
 ?
ATP + D-gluconate and ATP Pseudomonas sp. ADP + 6-phospho-D-gluconate
-
 ?

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
30
-
 assay at Pseudomonas sp.

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.8 8.2
-
 Pseudomonas sp.