Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
mitochondrion | - |
Homo sapiens | 5739 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + deoxyguanosine | Homo sapiens | - |
ADP + dGMP | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
U2OS cell | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + deoxyguanosine | - |
Homo sapiens | ADP + dGMP | - |
? |
Synonyms | Comment | Organism |
---|---|---|
DGK | - |
Homo sapiens |
Organism | Comment | Expression |
---|---|---|
Homo sapiens | treatment with 3'-azido-2',3'-dideoxythymidine (zidovudine) treatment leads to downregulation of the mitochondrial enzyme in U2OS cells. Incubation with 1 mM tert-butylhydroperoxide results in 80% and 65% reductions in mitochondrial protein levels. Similarly, incubation with 2 mM diamide leads to about 50% decreases in enzyme expression | down |