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Literature summary for 2.7.1.113 extracted from

  • Krawiec, K.; Kierdaszuk, B.; Kalinichenko, E.N.; Rubinova, E.B.; Mikhailopulo, I.A.; Eriksson, S.; Munch-Petersen, B.; Shugar, D.
    Ability of adenosine-2'(3')-deoxy-3'(2')-triphosphates and related analogues to replace ATP as phosphate donor for all human and Drosphila melanogaster deoxyribonucleoside kinases (2003), Nucleosides Nucleotides Nucleic Acids, 22, 1525-1529.
    View publication on PubMed

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+
-
Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
0.023
-
substrate 2'-deoxyguanosine and ATP Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2'-deoxyadenosine-3'-fluoro-3'-triphosphate + 2'-deoxyguanosine
-
Homo sapiens 2'-deoxyadenosine-3'-fluoro-3'-diphosphate + 2'-deoxyguanosine 5'-phosphate
-
?
2'-deoxyadenosine-3'-fluoroara-3'-triphosphate + 2'-deoxyguanosine low activity Homo sapiens 2'-deoxyadenosine-3'-fluoroara-3'-diphosphate + 2'-deoxyguanosine 5'-phosphate
-
?
2'-deoxyadenosine-3'-triphosphate + 2'-deoxyguanosine
-
Homo sapiens 2'-deoxyadenosine-3'-diphosphate + 2'-deoxyguanosine 5'-phosphate
-
?
3'-deoxyadenosine-2'-triphosphate + 2'-deoxyguanosine
-
Homo sapiens 3'-deoxyadenosine-2'-diphosphate + 2'-deoxyguanosine 5'-phosphate
-
?
3'-deoxyadenosine-3'-fluoro-2'-triphosphate + 2'-deoxyguanosine
-
Homo sapiens 3'-deoxyadenosine-3'-fluoro-2'-diphosphate + 2'-deoxyguanosine 5'-phosphate
-
?
3'-deoxyadenosine-3'-fluoroxylo-2'-triphosphate + 2'-deoxyguanosine
-
Homo sapiens 3'-deoxyadenosine-3'-fluoroxylo-2'-diphosphate + 2'-deoxyguanosine 5'-phosphate
-
?
ATP + 2'-deoxyguanosine
-
Homo sapiens ADP + 2'-deoxyguanosine 5'-phosphate
-
?

Synonyms

Synonyms Comment Organism
DGK
-
Homo sapiens

Cofactor

Cofactor Comment Organism Structure
2'-deoxyadenosine-3'-fluoro-3'-triphosphate 70% of the activity with ATP Homo sapiens
2'-deoxyadenosine-3'-fluoroara-3'-triphosphate 13% of the activity with ATP Homo sapiens
2'-deoxyadenosine-3'-triphosphate 53% of the activity with ATP Homo sapiens
3'-deoxyadenosine-2'-triphosphate 119% of the activity with ATP Homo sapiens
3'-deoxyadenosine-3'-fluoro-2'-triphosphate 25% of the activity with ATP Homo sapiens
3'-deoxyadenosine-3'-fluoroxylo-2'-triphosphate 55% of the activity with ATP Homo sapiens
ATP
-
Homo sapiens