Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + D-fructose 6-phosphate | Rattus norvegicus | - |
ADP + D-fructose 1,6-bisphosphate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | P47858 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
C6 glioma cell | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + D-fructose 6-phosphate | - |
Rattus norvegicus | ADP + D-fructose 1,6-bisphosphate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
PFK1 | - |
Rattus norvegicus |
phosphofructokinase 1 | - |
Rattus norvegicus |
Organism | Comment | Expression |
---|---|---|
Rattus norvegicus | after 48 h of the chemically induced hypoxia induction of the C6 glioma cells, the PFK1 protein depicts strong up regulation, with no appreciable change in its mRNA levels. The presence of a weak internal ribosome entry site (IRES) element in the 5'UTR of the PFK1 mRNA. The weak IRES element of the PFK1 is strongly up regulated after 48 h of the chemically induced hypoxia, indicative of a possible mechanism responsible for the induction of the PFK1 protein | up |
General Information | Comment | Organism |
---|---|---|
physiological function | phosphofructokinase1 (PFK1) is the major regulatory enzyme of the glycolytic pathway | Rattus norvegicus |