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Literature summary for 2.7.1.108 extracted from

  • Orlowski, J.; Machula, K.; Janik, A.; Zdebska, E.; Palamarczyk, G.
    Dissecting the role of dolichol in cell wall assembly in the yeast mutants impaired in early glycosylation reactions (2007), Yeast, 24, 239-252.
    View publication on PubMed
Search for more literature for 2.7.1.108

Protein Variants

Protein Variants Comment Organism
W332G mutated Sec59-1p bears the single amino acid substitution Trp(332) to Gly, region predicted to be responsible for the substrate (dolichol) binding Saccharomyces cerevisiae

Localization

Localization Comment Organism GeneOntology No. Textmining

Organism

Organism UniProt Comment Textmining
Saccharomyces cerevisiae
-
 temperature-sensitive Saccharomyces cerevisiae mutants, impaired in dolichol kinase (Sec59p) or dolichyl phosphate mannose synthase (Dpm1p) activity have an aberrant cell wall composition and ultrastructure
-
Saccharomyces cerevisiae
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 (Ferro-Novick et al., 1984), temperature sensitive mutants, mutants impaired in Sec59p (sec59-1), cells are defective in CTP-dependent dolichol kinase
-
Saccharomyces cerevisiae SF402-4D
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 (Ferro-Novick et al., 1984), temperature sensitive mutants, mutants impaired in Sec59p (sec59-1), cells are defective in CTP-dependent dolichol kinase
-

Source Tissue

Source Tissue Comment Organism Textmining
cell culture temperature-sensitive Saccharomyces cerevisiae mutants, impaired in dolichol kinase (Sec59p) or dolichyl phosphate mannose synthase (Dpm1p) activity have an aberrant cell wall composition and ultrastructure Saccharomyces cerevisiae
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
CTP + dolichol
-
 Saccharomyces cerevisiae CDP + dolichyl phosphate
-
 ?
CTP + dolichol
-
 Saccharomyces cerevisiae SF402-4D CDP + dolichyl phosphate
-
 ?

Synonyms

Synonyms Comment Organism
cytidine-5-triphosphate (CTP) dependent dolichol kinase
-
 Saccharomyces cerevisiae
Sec59p
-
 Saccharomyces cerevisiae

Cofactor

Cofactor Comment Organism Structure
CTP cytidine-5'-triphosphate Saccharomyces cerevisiae