Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + 1,2-diacyl-sn-glycerol | Mus musculus | - |
ADP + 1,2-diacyl-sn-glycerol 3-phosphate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | E9PUQ8 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
C2C12 cell | - |
Mus musculus | - |
myoblast | - |
Mus musculus | - |
skeletal muscle | - |
Mus musculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + 1,2-diacyl-sn-glycerol | - |
Mus musculus | ADP + 1,2-diacyl-sn-glycerol 3-phosphate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
DGKdelta | isoform | Mus musculus |
diacylglycerol kinase delta | isoform | Mus musculus |
Organism | Comment | Expression |
---|---|---|
Mus musculus | DGKdelta expression is down-regulated in the early stage of C2C12 myogenic differentiation | down |
General Information | Comment | Organism |
---|---|---|
malfunction | the suppression of DGKdelta expression increases the phosphorylation levels of conventional and novel protein kinase C (cnPKCs). Furthermore, DGKdelta suppression increases the levels of cyclin D1 and phospho-cnPKCs even at the first 24 h of myogenic differentiation | Mus musculus |
physiological function | isoform DGKdelta regulates the early differentiation of C2C12 myoblasts via controlling the down-regulation of cyclin D1 expression | Mus musculus |