Application | Comment | Organism |
---|---|---|
medicine | bifunctional 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 mRNA expression is greater in metastatic prostate cancer compared with primary tumors | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | Q16877 | bifunctional 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | - |
Organism | Comment | Expression |
---|---|---|
Homo sapiens | bifunctional 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 mRNA expression is greater in metastatic prostate cancer compared with primary tumors | up |
General Information | Comment | Organism |
---|---|---|
physiological function | enzyme is required to balance glycolytic activity and antioxidant production to maintain cellular redox balance in prostate cancer cells. Depletion of the enzyme inhibits tumor growth in a xenograft model, indicating that it is required under physiologic nutrient levels. Enzyme mRNA expression is greater in metastatic prostate cancer compared with primary tumors | Homo sapiens |