Activating Compound | Comment | Organism | Structure |
---|---|---|---|
iodoacetamide | - |
Rattus norvegicus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
additional information | phosphorylation by cAMP-dependent protein kinase causes inactivation of liver enzyme; phosphorylation of foetal liver enzyme by protein kinase C, but no effect on adult liver cells | Rattus norvegicus | |
sn-glycerol 3-phosphate | stimulates phosphatase activity | Rattus norvegicus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.044 | - |
beta-D-fructose 6-phosphate | pH 8.5, 30°C, foetal liver enzyme | Rattus norvegicus | |
0.047 | - |
beta-D-fructose 6-phosphate | pH 8.5, 30°C, adult liver enzyme | Rattus norvegicus | |
0.19 | - |
ATP | pH 8.5, 30°C, foetal enzyme | Rattus norvegicus | |
0.195 | - |
ATP | pH 8.5, 30°C, adult enzyme | Rattus norvegicus |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mg2+ | MgATP2 | Rattus norvegicus |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
55000 | - |
2 * 55000, SDS-PAGE | Rattus norvegicus |
89100 | - |
foetal liver, gel filtration | Rattus norvegicus |
100000 | - |
adult liver, gel filtration | Rattus norvegicus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
foetal and adult | - |
Posttranslational Modification | Comment | Organism |
---|---|---|
phosphoprotein | phosphorylation of foetal liver enzyme by protein kinase C, but no effect on adult liver cells | Rattus norvegicus |
phosphoprotein | phosphorylation by cAMP-dependent protein kinase causes inactivation of liver enzyme | Rattus norvegicus |
Purification (Comment) | Organism |
---|---|
- |
Rattus norvegicus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Rattus norvegicus | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
0.055 | - |
adult | Rattus norvegicus |
0.08 | - |
foetal | Rattus norvegicus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + beta-D-fructose 6-phosphate | - |
Rattus norvegicus | ADP + beta-D-fructose 2,6-bisphosphate | - |
? |
Subunits | Comment | Organism |
---|---|---|
dimer | 2 * 55000, SDS-PAGE | Rattus norvegicus |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.15 | - |
sn-glycerol 3-phosphate | pH 7.1 | Rattus norvegicus |