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Literature summary for 2.7.1.105 extracted from
- Inhibition of rat liver phosphofructokinase-2 by phosphoenolpyruvate and ADP (1984), Biochem. Biophys. Res. Commun., 124, 793-796.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| ADP | kinetics | Rattus norvegicus |  |
| phosphoenolpyruvate | kinetics | Rattus norvegicus | |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.09 | - |
beta-D-fructose 6-phosphate | pH 6.6, 25°C | Rattus norvegicus | |
| 0.4 | - |
ATP | pH 6.6, 25°C | Rattus norvegicus | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| liver | - |
Rattus norvegicus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + beta-D-fructose 6-phosphate | - |
Rattus norvegicus | ADP + beta-D-fructose 2,6-bisphosphate | - |
? | |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 25 | - |
assay at | Rattus norvegicus |
Ki Value [mM]
| Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.16 | - |
ADP | pH 6.6, 25°C | Rattus norvegicus | |
| 2.3 | - |
phosphoenolpyruvate | pH 6.6, 25°C | Rattus norvegicus | |
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