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Literature summary for 2.7.1.105 extracted from
- Partial purification of a rat liver enzyme that catalyzes the formation of fructose 2,6-bisphosphate (1981), Biochem. Biophys. Res. Commun., 101, 1071-1077.
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.2 | - |
ATP | pH 7.5, 22°C | Rattus norvegicus |  |
| 0.5 | - |
MgATP2- | pH 7.5, 30°C | Rattus norvegicus | |
| 0.5 | - |
beta-D-fructose 6-phosphate | pH 7.5, 22°C | Rattus norvegicus | |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| cytosol | - |
Rattus norvegicus | 5829 | - |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Mg2+ | MgATP2 | Rattus norvegicus | |
| Mg2+ | MgGTP2 | Rattus norvegicus | |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 85000 | 90000 | gel filtration | Rattus norvegicus |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| partial | Rattus norvegicus |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| liver | - |
Rattus norvegicus | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| 0.0005 | - |
- |
Rattus norvegicus |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + beta-D-fructose 6-phosphate | transfers gamma-phosphoryl group of ATP to hydroxyl group at C-2 of fructose 6-phosphate | Rattus norvegicus | ADP + beta-D-fructose 2,6-bisphosphate | - |
? | |
| ATP + beta-D-fructose 6-phosphate | no substrates are diphosphate, glucose 6-phosphate | Rattus norvegicus | ADP + beta-D-fructose 2,6-bisphosphate | - |
? | |
| ATP + beta-D-fructose 6-phosphate | not: ribose 5-phosphate | Rattus norvegicus | ADP + beta-D-fructose 2,6-bisphosphate | - |
? | |
| GTP + beta-D-fructose 6-phosphate | less effective than ATP | Rattus norvegicus | GDP + beta-D-fructose 2,6-bisphosphate | - |
? | |
| MgATP2- + beta-D-fructose 6-phosphate | - |
Rattus norvegicus | ? | - |
? | |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 22 | - |
assay at | Rattus norvegicus |
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Release 2023.1 (January 2023)
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