Literature summary for 2.7.1.1 extracted from

Khan, M.W.; Ding, X.; Cotler, S.J.; Clarke, M.; Layden, B.T.
Studies on the tissue localization of HKDC1, a putative novel fifth hexokinase, in humans (2018), J. Histochem. Cytochem., 66, 385-392 .

Search for more literature for 2.7.1.1

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	Q2TB90	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
cardiac muscle	low expression	Homo sapiens	-
colon	high expression in surface epithelium. Very low expression in crypt base epithelium	Homo sapiens	-
epidermis	very low expression	Homo sapiens	-
esophageal squamous epithelium	intermediate expression in suprabasal squamous epithelium. Low expression in basal layer	Homo sapiens	-
hair follicle	low expression	Homo sapiens	-
intestine	high expression in villous brush border. No expression in deep crypt epithelium	Homo sapiens	-
kidney	low expression	Homo sapiens	-
liver	no expression in hepatocytes. Very low expression in interlobular bile duct	Homo sapiens	-
lung	high expression in alveolar macrophages. Intermediate expression in bronchial epithelium. very low expression in alveolar lining cells	Homo sapiens	-
myenteric plexus	low expression	Homo sapiens	-
pancreas	high expression in acinar centrocytes, onterlobular pancreatic duct and larger pancreatic duct. Very low expression in pancreatic islet cells. No expression in acinar cells	Homo sapiens	-
prostate gland	intermediate expression in basal cells. Low to intermediate expression in stromal cells. Low expression in gland epithelium	Homo sapiens	-
skeletal muscle	low expression	Homo sapiens	-
spleen	low expression	Homo sapiens	-
stomach	high expression in parietal cells and chief cells. Intermediate expression in superficial foveolar epithelium	Homo sapiens	-
sweat gland	low expression in sweat gland, intermediate expression in sweat gland duct	Homo sapiens	-
testis	low expression	Homo sapiens	-
thyroid gland	intermediate to high expression	Homo sapiens	-

Synonyms

Synonyms	Comment	Organism
HKDC1	-	Homo sapiens

General Information

General Information	Comment	Organism
physiological function	the enzyme is important during pregnancy in the regulation of glucose homeostasis	Homo sapiens

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Release 2023.1 (January 2023)