Literature summary for 2.7.1.1 extracted from

Milanes, J.E.; Suryadi, J.; Abendroth, J.; Van Voorhis, W.C.; Barrett, K.F.; Dranow, D.M.; Phan, I.Q.; Patrick, S.L.; Rozema, S.D.; Khalifa, M.M.; Golden, J.E.; Morris, J.C.
Enzymatic and structural characterization of the Naegleria fowleri glucokinase (2019), Antimicrob. Agents Chemother., 63, e02410-18 .

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Inhibitors

Inhibitors	Comment	Organism	Structure
N,N'-[furan-2,5-diylbis(2-chloro-4,1-phenylene)]diguanidine	-	Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
ATP + D-glucose	Homo sapiens	-	ADP + D-glucose 6-phosphate	-	?

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	P35557	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
ATP + D-glucose	-	Homo sapiens	ADP + D-glucose 6-phosphate	-	?

Synonyms

Synonyms	Comment	Organism
NfGlck	-	Homo sapiens

IC50 Value

IC50 Value	IC50 Value Maximum	Comment	Organism	Inhibitor	Structure
0.00026	-	pH and temperature not specified in the publication	Homo sapiens	N,N'-[furan-2,5-diylbis(2-chloro-4,1-phenylene)]diguanidine

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Release 2023.1 (January 2023)