Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 2.7.1.1 extracted from

  • Kim, Y.B.; Kalinowski, S.S.; Marcinkeviciene, J.
    A pre-steady state analysis of ligand binding to human glucokinase: evidence for a preexisting equilibrium (2007), Biochemistry, 46, 1423-1431.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
palmitoyl-CoA
-
Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + D-glucose Homo sapiens control of GK activity and Km through the ratio of distinct conformers (super-open, open, and closed) through either substrate or other ligand binding and/or dissociation ADP + D-glucose 6-phosphate
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
recombinant
-

Purification (Commentary)

Purification (Comment) Organism
recombinant Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + D-glucose
-
Homo sapiens ADP + D-glucose 6-phosphate
-
?
ATP + D-glucose control of GK activity and Km through the ratio of distinct conformers (super-open, open, and closed) through either substrate or other ligand binding and/or dissociation Homo sapiens ADP + D-glucose 6-phosphate
-
?

Synonyms

Synonyms Comment Organism
glucokinase
-
Homo sapiens