Activating Compound | Comment | Organism | Structure |
---|---|---|---|
galactose | activates isoenzyme Hex II | Candida maltosa | |
isocitrate | activates isoenzyme Hex II | Candida maltosa | |
lyxose | activates isoenzyme Hex II | Candida maltosa | |
mannose 6-phosphate | activates isoenzyme Hex II | Candida maltosa | |
phosphoenolpyruvate | activates isoenzyme Hex I | Candida maltosa | |
ribose | activates isoenzyme Hex II | Candida maltosa | |
xylose | activates isoenzyme Hex II | Candida maltosa |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
ADP | - |
Candida maltosa | |
D-mannose | - |
Candida maltosa |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
additional information | - |
additional information | - |
Candida maltosa |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mg2+ | required | Candida maltosa | |
Mg2+ | below 3 mM | Candida maltosa |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
96000 | - |
Hex II, gel filtration | Candida maltosa |
110000 | - |
gel filtration | Candida maltosa |
110000 | - |
Hex I | Candida maltosa |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
D-glucose + ATP | Candida maltosa | isoenzymes are a target for effective control of glucose 6-phosphate formation by energy charge of the cell or by the intracellular level of ATP, ADP and glucose instead of allosteric interconversions of the enzyme | D-glucose 6-phosphate + ADP | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Candida maltosa | - |
H, isoenzymes Hex I and Hex II | - |
Purification (Comment) | Organism |
---|---|
isoenzymes Hex I and Hex II, partial | Candida maltosa |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
additional information | - |
- |
Candida maltosa |
0.11 | 0.16 | Hex I and II, at pH 8.2 | Candida maltosa |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
D-glucose + ATP | specific for ATP | Candida maltosa | ADP + D-glucose 6-phosphate | - |
? | |
D-glucose + ATP | isoenzymes are a target for effective control of glucose 6-phosphate formation by energy charge of the cell or by the intracellular level of ATP, ADP and glucose instead of allosteric interconversions of the enzyme | Candida maltosa | D-glucose 6-phosphate + ADP | - |
? | |
D-mannose + ATP | - |
Candida maltosa | ADP + D-mannose 6-phosphate | - |
? | |
additional information | not: UTP | Candida maltosa | ? | - |
? | |
additional information | not: ITP | Candida maltosa | ? | - |
? | |
additional information | not: GTP | Candida maltosa | ? | - |
? |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.5 | 8.5 | isoenzyme Hex II | Candida maltosa |
7.5 | 8.2 | isoenzyme Hex I | Candida maltosa |
8.2 | - |
assay at | Candida maltosa |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
ATP | - |
Candida maltosa |