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Literature summary for 2.6.1.99 extracted from

  • Won, C.; Shen, X.; Mashiguchi, K.; Zheng, Z.; Dai, X.; Cheng, Y.; Kasahara, H.; Kamiya, Y.; Chory, J.; Zhao, Y.
    Conversion of tryptophan to indole-3-acetic acid by TRYPTOPHAN AMINOTRANSFERASES OF ARABIDOPSIS and YUCCAs in Arabidopsis (2011), Proc. Natl. Acad. Sci. USA, 108, 18518-18523.
    View publication on PubMedView publication on EuropePMC
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Protein Variants

Protein Variants Comment Organism
additional information construction of taa mutants showing phenotypes including defects in shade avoidance, root resistance to ethylene and N-1-naphthylphthalamic acid, the phenotypess are phenocopied by inactivating YUC genes, overview. Overexpression of YUC1 partially suppresses the shade avoidance defects of taa1 and the sterile phenotypes of the weak but not the strong taa mutants. The auxin overproduction phenotypes of YUC overexpression lines are dependent on active TAA genes. Construcction of wei8 tar2 mutants, phenotypes, overview Arabidopsis thaliana

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
L-tryptophan + pyruvate Arabidopsis thaliana
-
 indole-3-pyruvate + L-alanine
-
 ?

Organism

Organism UniProt Comment Textmining
Arabidopsis thaliana
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
root
-
 Arabidopsis thaliana
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-tryptophan + pyruvate
-
 Arabidopsis thaliana indole-3-pyruvate + L-alanine
-
 ?

Synonyms

Synonyms Comment Organism
TAA
-
 Arabidopsis thaliana
tryptophan aminotransferase of Arabidopsis 1
-
 Arabidopsis thaliana

General Information

General Information Comment Organism
malfunction taa mutants are partially indole-3-pyruvate-deficient, indicating that TAAs are responsible for converting tryptophan to indole-3-pyruvate. Inactivation of TAA1/TIR2 causes root resistance to the auxin transport inhibitor naphthylphthalamic acid Arabidopsis thaliana
metabolism tryptophan aminotransferase of Arabidopsis thaliana, TAA, and YUCCA work in the same pathway and that YUC is downstream of TAA. The TAA family of amino transferases converts tryptophan to indole-3-pyruvate, and the YUC family of flavin monooxygenases participates in converting IPA to indole-3-acetic acid, the main auxin in plants Arabidopsis thaliana
additional information taa mutants show phenotypes including defects in shade avoidance, root resistance to ethylene and N-1-naphthylphthalamic acid, the phenotypes are phenocopied by inactivating YUC genes, overview Arabidopsis thaliana