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Literature summary for 2.6.1.92 extracted from

  • Schoenhofen, I.C.; McNally, D.J.; Vinogradov, E.; Whitfield, D.; Young, N.M.; Dick, S.; Wakarchuk, W.W.; Brisson, J.R.; Logan, S.M.
    Functional characterization of dehydratase/aminotransferase pairs from Helicobacter and Campylobacter: enzymes distinguishing the pseudaminic acid and bacillosamine biosynthetic pathways (2006), J. Biol. Chem., 281, 723-732.
    View publication on PubMed
Search for more literature for 2.6.1.92

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.052
-
 UDP-2-acetamido-2,6-dideoxy-beta-L-arabino-hex-4-ulose pH 7.7, 37°C Campylobacter jejuni

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
UDP-2-acetamido-2,6-dideoxy-beta-L-arabino-hex-4-ulose + L-glutamate Campylobacter jejuni the enzyme is involved biosynthesis of pseudaminic acid UDP-4-amino-4,6-dideoxy-L-N-acetyl-beta-L-altrosamine + 2-oxoglutarate
-
 ?
UDP-2-acetamido-2,6-dideoxy-beta-L-arabino-hex-4-ulose + L-glutamate Helicobacter pylori the enzyme is involved biosynthesis of pseudaminic acid UDP-4-amino-4,6-dideoxy-L-N-acetyl-beta-L-altrosamine + 2-oxoglutarate
-
 ?
UDP-2-acetamido-2,6-dideoxy-beta-L-arabino-hex-4-ulose + L-glutamate Campylobacter jejuni 11168 the enzyme is involved biosynthesis of pseudaminic acid UDP-4-amino-4,6-dideoxy-L-N-acetyl-beta-L-altrosamine + 2-oxoglutarate
-
 ?

Organism

Organism UniProt Comment Textmining
Campylobacter jejuni
-
-
-
Helicobacter pylori O25130
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
UDP-2-acetamido-2,6-dideoxy-beta-L-arabino-hex-4-ulose + L-glutamate
-
 Helicobacter pylori UDP-4-amino-4,6-dideoxy-L-N-acetyl-beta-L-altrosamine + 2-oxoglutarate
-
 ?
UDP-2-acetamido-2,6-dideoxy-beta-L-arabino-hex-4-ulose + L-glutamate the enzyme is involved biosynthesis of pseudaminic acid Campylobacter jejuni UDP-4-amino-4,6-dideoxy-L-N-acetyl-beta-L-altrosamine + 2-oxoglutarate
-
 ?
UDP-2-acetamido-2,6-dideoxy-beta-L-arabino-hex-4-ulose + L-glutamate the enzyme is involved biosynthesis of pseudaminic acid Helicobacter pylori UDP-4-amino-4,6-dideoxy-L-N-acetyl-beta-L-altrosamine + 2-oxoglutarate
-
 ?
UDP-2-acetamido-2,6-dideoxy-beta-L-arabino-hex-4-ulose + L-glutamate the enzyme (Cj1294) does not utilize UDP-2-acetamido-2,6-dideoxy-alpha-D-xylo-4-hexulose as substrate Campylobacter jejuni UDP-4-amino-4,6-dideoxy-L-N-acetyl-beta-L-altrosamine + 2-oxoglutarate
-
 ?
UDP-2-acetamido-2,6-dideoxy-beta-L-arabino-hex-4-ulose + L-glutamate the enzyme is involved biosynthesis of pseudaminic acid Campylobacter jejuni 11168 UDP-4-amino-4,6-dideoxy-L-N-acetyl-beta-L-altrosamine + 2-oxoglutarate
-
 ?
UDP-2-acetamido-2,6-dideoxy-beta-L-arabino-hex-4-ulose + L-glutamate the enzyme (Cj1294) does not utilize UDP-2-acetamido-2,6-dideoxy-alpha-D-xylo-4-hexulose as substrate Campylobacter jejuni 11168 UDP-4-amino-4,6-dideoxy-L-N-acetyl-beta-L-altrosamine + 2-oxoglutarate
-
 ?

Synonyms

Synonyms Comment Organism
Cj1294
-
 Campylobacter jejuni
HP0366
-
 Helicobacter pylori

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
 assay at Campylobacter jejuni
37
-
 assay at Helicobacter pylori

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
0.067
-
 UDP-2-acetamido-2,6-dideoxy-beta-L-arabino-hex-4-ulose pH 7.7, 37°C Campylobacter jejuni

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.7
-
 assay at Campylobacter jejuni
7.7
-
 assay at Helicobacter pylori

Cofactor

Cofactor Comment Organism Structure
pyridoxal 5'-phosphate a pyridoxal 5'-phosphate protein Campylobacter jejuni
pyridoxal 5'-phosphate a pyridoxal 5'-phosphate protein Helicobacter pylori