BRENDA - Reference to 2.6.1.85; Id = 661938

2-fluorochorismate

irreversible, covalent modification of K274

Escherichia coli

-

chorismate + L-glutamine = 4-amino-4-deoxychorismate + L-glutamate

omega-amino group of K274 adds to chorismate at C2, leading to elimination of the C4 hydroxyl in an SN2'' displacement reaction. After attack of ammonia to intermediate, another SN2'' displacement expels K274 and forms aminodeoxychorismate

Escherichia coli

dimer

heterodimer of chorismate aminating subunit and glutamine amidotransferase subunit. Mass of glutamine amidotransferase subunit is 50969 Da, as determined by electrospray mass spectrometry

Escherichia coli

0.13

-

2-fluorochorismate

-

Escherichia coli

2-fluorochorismate

irreversible, covalent modification of K274

Escherichia coli

0.13

-

2-fluorochorismate

-

Escherichia coli

dimer

heterodimer of chorismate aminating subunit and glutamine amidotransferase subunit. Mass of glutamine amidotransferase subunit is 50969 Da, as determined by electrospray mass spectrometry

Escherichia coli

737705

Culbertson

Conversion of aminodeoxychoris ...

Escherichia coli

Biochemistry

54

2372-2384

2015

-

1

-

3

-

5

-

1

-

3

-

738864

Deng

Cloning, expression, and chara ...

Agaricus bisporus

J. Microbiol. Biotechnol.

25

66-73

2015

-

1

-

2

-

3

1

-

3

-

3

1

-

2

1

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1

-

2

-

3

1

-

3

1

-

2

1

-

2

724464

Culbertson

Expression and characterizatio ...

Pseudomonas aeruginosa

Biochim. Biophys. Acta

1834

240-246

2013

-

4

3

-

3

1

-

5

-

3

1

-

2

1

-

4

-

3

-

3

1

-

3

1

-

2

1

-

724331

Bera

Structure of aminodeoxychorism ...

Stenotrophomonas maltophilia

Biochemistry

51

10208-10217

2012

-

1

-

1

-

1

-

3

-

1

-

2

1

-

2

-

1

-

1

-

1

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1

-

1

-

2

1

-

2

-

724111

Camara

The synthesis of pABA: Couplin ...

Arabidopsis thaliana

Arch. Biochem. Biophys.

505

83-90

2011

1

-

1

-

1

7

1

-

3

-

1

-

2

-

1

4

-

1

-

1

-

1

-

1

7

1

-

1

-

2

-

1

4

-

6

702371

Ziebart

Nucleophile specificity in ant ...

Escherichia coli

Biochemistry

49

2851-2859

2010

-

1

-

2

-

1

-

1

-

1

-

2

-

1

-

2

-

1

-

1

-

2

-

684435

Keller

Action of atrop-abyssomicin C ...

Bacillus subtilis

Angew. Chem. Int. Ed. Engl.

46

8284-8286

2007

-

1

-

1

-

1

-

661933

He

Conservation of mechanism in t ...

Escherichia coli

J. Am. Chem. Soc.

126

2378-2385

2004

-

1

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2

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1

5

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3

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1

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2

-

6

-

2

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1

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2

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1

2

5

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2

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6

-

661938

Bulloch

Identification of 4-amino-4-de ...

Escherichia coli

J. Am. Chem. Soc.

126

9912-9913

2004

-

1

-

1

-

1

-

1

-

1

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1

-

1

-

644249

Parsons

Structure of Escherichia coli ...

Escherichia coli

Biochemistry

41

2198-2208

2002

-

1

-

1

-

1

-

2

-

1

-

1

2

1

-

1

-

1

-

1

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1

-

1

2

1

-

644250

Chang

p-Aminobenzoic acid and chlora ...

Streptomyces venezuelae, Streptomyces venezuelae ISP5230

Microbiology

147

2113-2126

2001

-

1

-

2

-

8

-

2

-

1

-

2

-

2

-

644248

Rayl

Escherichia coli aminodeoxycho ...

Escherichia coli

Biochim. Biophys. Acta

1295

81-88

1996

-

1

-

2

-

1

-

2

-

1

-

2

-

644230

Viswanathan

Kinetic characterization of 4- ...

Escherichia coli

J. Bacteriol.

177

5918-5923

1995

2

-

1

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1

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2

-

1

-

1

-

1

-

2

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1

-

1

-

1

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1

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1

-

644227

Ye

p-Aminobenzoate synthesis in E ...

Escherichia coli

Proc. Natl. Acad. Sci. USA

87

9391-9395

1990

-

1

-

1

-

1

-

2

-

1

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1

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1

-

1

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1

-

1

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1

-

Identification of 4-amino-4-deoxychorismate synthase as the molecular target for the antimicrobial action of (6S)-6-fluoroshikimate

Data extracted from this reference: