Literature summary for 2.6.1.81 extracted from

Stalon, V.; Vander Wauven, C.; Momin, P.; Legrain, C.
Catabolism of arginine, citrulline and ornithine by Pseudomonas and related bacteria (1987), J. Gen. Microbiol., 133, 2487-2495.

Activating Compound

Activating Compound	Comment	Organism
additional information	arginine induces the enzymes of the entire pathway, while citrulline, and ornithine suppress them	Pseudomonas putida
additional information	arginine induces the enzymes of the entire pathway, while citrulline, and ornithine suppress them	Trinickia caryophylli
additional information	arginine induces the enzymes of the entire pathway, while glutamate and ornithine suppress them	Pseudomonas chlororaphis subsp. aureofaciens
additional information	arginine induces the enzymes of the entire pathway, while glutamate, and ornithine suppress them	Oceanimonas doudoroffii
additional information	arginine induces the enzymes of the entire pathway, while ornithine, glucose and ammonium suppress them	Pseudomonas aeruginosa
additional information	arginine induces the enzymes of the entire pathway, while ornithine, glucose, and ammonium suppress them	Pseudomonas formicans
additional information	arginine induces the enzymes of the entire pathway, while ornithine, succinate and ammonium suppress them	Pseudomonas fluorescens
additional information	arginine induces the enzymes of the entire pathway, while ornithine, succinate and ammonium suppress them	Pseudomonas mendocina
additional information	arginine induces the enzymes of the entire pathway, while succinate and ammonium suppress them	Pseudomonas aeruginosa
additional information	arginine induces the enzymes of the entire pathway, while succinate and ammonium suppress them	Vogesella indigofera
additional information	arginine induces the enzymes of the entire pathway, while succinate, citrulline, ornithine, and ammonium suppress them	Burkholderia cepacia

Inhibitors

Inhibitors	Comment	Organism
additional information	arginine induces the enzymes of the entire pathway, while succinate, citrulline, ornithine, and ammonium suppress them	Burkholderia cepacia
additional information	arginine induces the enzymes of the entire pathway, while glutamate, and ornithine suppress them	Oceanimonas doudoroffii
additional information	arginine induces the enzymes of the entire pathway, while ornithine, glucose and ammonium suppress them; arginine induces the enzymes of the entire pathway, while succinate and ammonium suppress them	Pseudomonas aeruginosa
additional information	arginine induces the enzymes of the entire pathway, while glutamate and ornithine suppress them	Pseudomonas chlororaphis subsp. aureofaciens
additional information	arginine induces the enzymes of the entire pathway, while ornithine, succinate and ammonium suppress them	Pseudomonas fluorescens
additional information	arginine induces the enzymes of the entire pathway, while ornithine, glucose, and ammonium suppress them	Pseudomonas formicans
additional information	arginine induces the enzymes of the entire pathway, while ornithine, succinate and ammonium suppress them	Pseudomonas mendocina
additional information	arginine induces the enzymes of the entire pathway, while citrulline, and ornithine suppress them	Pseudomonas putida
additional information	arginine induces the enzymes of the entire pathway, while glutamate suppresses them	Trinickia caryophylli
additional information	arginine induces the enzymes of the entire pathway, while ornithine, citrulline, and glutamate suppress them	Vogesella indigofera

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.
N2-succinyl-L-ornithine + 2-oxoglutarate	Burkholderia cepacia	key enzyme in the group of pdx gene-encoded enzymes involved in the de novo synthesis of vitamin B6	N-succinyl-L-glutamate 5-semialdehyde + L-glutamate	-	?
N2-succinyl-L-ornithine + 2-oxoglutarate	Pseudomonas fluorescens	step in metabolic conversion of L-arginine into L-glutamate, pathway succinylornithine and competing pathways overview	N-succinyl-L-glutamate 5-semialdehyde + L-glutamate	-	?
N2-succinyl-L-ornithine + 2-oxoglutarate	Pseudomonas aeruginosa	step in metabolic conversion of L-arginine into L-glutamate, pathway succinylornithine and competing pathways overview	N-succinyl-L-glutamate 5-semialdehyde + L-glutamate	-	?
N2-succinyl-L-ornithine + 2-oxoglutarate	Pseudomonas putida	step in metabolic conversion of L-arginine into L-glutamate, pathway succinylornithine and competing pathways overview	N-succinyl-L-glutamate 5-semialdehyde + L-glutamate	-	?
N2-succinyl-L-ornithine + 2-oxoglutarate	Pseudomonas mendocina	step in metabolic conversion of L-arginine into L-glutamate, pathway succinylornithine and competing pathways overview	N-succinyl-L-glutamate 5-semialdehyde + L-glutamate	-	?
N2-succinyl-L-ornithine + 2-oxoglutarate	Pseudomonas chlororaphis subsp. aureofaciens	step in metabolic conversion of L-arginine into L-glutamate, pathway succinylornithine and competing pathways overview	N-succinyl-L-glutamate 5-semialdehyde + L-glutamate	-	?
N2-succinyl-L-ornithine + 2-oxoglutarate	Trinickia caryophylli	step in metabolic conversion of L-arginine into L-glutamate, pathway succinylornithine and competing pathways overview	N-succinyl-L-glutamate 5-semialdehyde + L-glutamate	-	?
N2-succinyl-L-ornithine + 2-oxoglutarate	Pseudomonas aeruginosa	step in metabolic conversion of L-arginine into L-glutamate, succinylornithine pathway and competing pathways, overview	N-succinyl-L-glutamate 5-semialdehyde + L-glutamate	-	?
N2-succinyl-L-ornithine + 2-oxoglutarate	Vogesella indigofera	step in metabolic conversion of L-arginine into L-glutamate, succinylornithine pathway and competing pathways, overview	N-succinyl-L-glutamate 5-semialdehyde + L-glutamate	-	?
N2-succinyl-L-ornithine + 2-oxoglutarate	Oceanimonas doudoroffii	step in metabolic conversion of L-arginine into L-glutamate, succinylornithine pathway and competing pathways, overview	N-succinyl-L-glutamate 5-semialdehyde + L-glutamate	-	?
N2-succinyl-L-ornithine + 2-oxoglutarate	Pseudomonas formicans	step in metabolic conversion of L-arginine into L-glutamate, succinylornithine pathway and competing pathways, overview	N-succinyl-L-glutamate 5-semialdehyde + L-glutamate	-	?

Organism

Organism	UniProt	Comment	Textmining
Burkholderia cepacia	-	-	-
Oceanimonas doudoroffii	-	-	-
Pseudomonas aeruginosa	-	-	-
Pseudomonas chlororaphis subsp. aureofaciens	-	-	-
Pseudomonas fluorescens	-	-	-
Pseudomonas formicans	-	-	-
Pseudomonas mendocina	-	-	-
Pseudomonas putida	-	-	-
Trinickia caryophylli	-	-	-
Vogesella indigofera	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
culture condition:arginine-grown cell	-	Pseudomonas fluorescens	-
culture condition:arginine-grown cell	-	Pseudomonas aeruginosa	-
culture condition:arginine-grown cell	-	Pseudomonas putida	-
culture condition:arginine-grown cell	-	Pseudomonas mendocina	-
culture condition:arginine-grown cell	-	Burkholderia cepacia	-
culture condition:arginine-grown cell	-	Vogesella indigofera	-
culture condition:arginine-grown cell	-	Oceanimonas doudoroffii	-
culture condition:arginine-grown cell	-	Pseudomonas chlororaphis subsp. aureofaciens	-
culture condition:arginine-grown cell	-	Trinickia caryophylli	-
culture condition:arginine-grown cell	-	Pseudomonas formicans	-
culture condition:citrulline-grown cell	-	Pseudomonas putida	-
culture condition:citrulline-grown cell	-	Burkholderia cepacia	-
culture condition:citrulline-grown cell	-	Vogesella indigofera	-
culture condition:glucose/ammonium-grown cell	-	Pseudomonas aeruginosa	-
culture condition:glucose/ammonium-grown cell	-	Pseudomonas formicans	-
culture condition:glutamate-grown cell	-	Vogesella indigofera	-
culture condition:glutamate-grown cell	-	Oceanimonas doudoroffii	-
culture condition:glutamate-grown cell	-	Pseudomonas chlororaphis subsp. aureofaciens	-
culture condition:glutamate-grown cell	-	Trinickia caryophylli	-
culture condition:ornithine-grown cell	-	Pseudomonas fluorescens	-
culture condition:ornithine-grown cell	-	Pseudomonas aeruginosa	-
culture condition:ornithine-grown cell	-	Pseudomonas putida	-
culture condition:ornithine-grown cell	-	Pseudomonas mendocina	-
culture condition:ornithine-grown cell	-	Burkholderia cepacia	-
culture condition:ornithine-grown cell	-	Vogesella indigofera	-
culture condition:ornithine-grown cell	-	Oceanimonas doudoroffii	-
culture condition:ornithine-grown cell	-	Pseudomonas chlororaphis subsp. aureofaciens	-
culture condition:ornithine-grown cell	-	Pseudomonas formicans	-
culture condition:succinate/ammonium-grown cell	-	Pseudomonas fluorescens	-
culture condition:succinate/ammonium-grown cell	-	Pseudomonas aeruginosa	-
culture condition:succinate/ammonium-grown cell	-	Pseudomonas putida	-
culture condition:succinate/ammonium-grown cell	-	Pseudomonas mendocina	-
culture condition:succinate/ammonium-grown cell	-	Burkholderia cepacia	-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg]	Specific Activity Maximum [µmol/min/mg]	Comment	Organism
0.017	-	glucose/ammonium-grown cells, cell extract	Pseudomonas aeruginosa
0.017	-	succinate/ammonium-grown cells, cell extract	Pseudomonas mendocina
0.025	-	succinate/ammonium-grown cells, cell extract	Pseudomonas aeruginosa
0.027	-	succinate/ammonium-grown cells, cell extract	Burkholderia cepacia
0.03	-	succinate/ammonium-grown cells, cell extract	Pseudomonas fluorescens
0.038	-	glucose/ammonium-grown cells, cell extract	Pseudomonas formicans
0.056	-	glutamate-grown cells, cell extract	Pseudomonas chlororaphis subsp. aureofaciens
0.07	-	glutamate-grown cells, induced enzyme, cell extract	Trinickia caryophylli
0.07	-	ornithine-grown cells, induced enzyme or succinate/ammonium-grown cells, cell extract	Pseudomonas putida
0.07	-	ornithine-grown cells, induced enzyme, cell extract	Pseudomonas mendocina
0.075	-	ornithine-grown cells, induced enzyme, cell extract	Pseudomonas aeruginosa
0.083	-	ornithine-grown cells, induced enzyme, cell extract	Pseudomonas fluorescens
0.09	-	citrulline-grown cells, induced enzyme, cell extract	Pseudomonas putida
0.11	-	ornithine-grown cells, induced enzyme, cell extract	Burkholderia cepacia
0.11	-	ornithine-grown cells, induced enzyme, cell extract	Pseudomonas chlororaphis subsp. aureofaciens
0.112	-	citrulline-grown cells, induced enzyme, cell extract	Burkholderia cepacia
0.14	-	glutamate-grown cells, cell extract	Vogesella indigofera
0.25	-	ornithine-grown cells, induced enzyme, cell extract	Oceanimonas doudoroffii
0.3	-	glutamate-grown cells, cell extract	Oceanimonas doudoroffii
0.33	-	arginine-grown cells, induced enzyme, cell extract	Pseudomonas putida
0.36	-	ornithine-grown cells, induced enzyme, cell extract	Pseudomonas aeruginosa
0.37	-	arginine-grown cells, induced enzyme, cell extract	Pseudomonas mendocina
0.57	-	citrulline-grown cells, induced enzyme, cell extract	Vogesella indigofera
0.58	-	ornithine-grown cells, induced enzyme, cell extract	Pseudomonas formicans
0.69	-	arginine-grown cells, induced enzyme, cell extract	Pseudomonas aeruginosa
0.77	-	arginine-grown cells, induced enzyme, cell extract	Pseudomonas fluorescens
0.9	-	arginine-grown cells, induced enzyme, cell extract	Pseudomonas chlororaphis subsp. aureofaciens
0.97	-	ornithine-grown cells, induced enzyme, cell extract	Vogesella indigofera
1.06	-	arginine-grown cells, induced enzyme, cell extract	Pseudomonas aeruginosa
1.07	-	arginine-grown cells, induced enzyme, cell extract	Burkholderia cepacia
1.12	-	arginine-grown cells, induced enzyme, cell extract	Pseudomonas formicans
1.38	-	arginine-grown cells, induced enzyme, cell extract	Oceanimonas doudoroffii
1.77	-	arginine-grown cells, induced enzyme, cell extract	Trinickia caryophylli
2.33	-	arginine-grown cells, induced enzyme, cell extract	Vogesella indigofera

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.
N2-succinyl-L-ornithine + 2-oxoglutarate	-	Pseudomonas fluorescens	N-succinyl-L-glutamate 5-semialdehyde + L-glutamate	-	?
N2-succinyl-L-ornithine + 2-oxoglutarate	-	Pseudomonas aeruginosa	N-succinyl-L-glutamate 5-semialdehyde + L-glutamate	-	?
N2-succinyl-L-ornithine + 2-oxoglutarate	-	Pseudomonas putida	N-succinyl-L-glutamate 5-semialdehyde + L-glutamate	-	?
N2-succinyl-L-ornithine + 2-oxoglutarate	-	Pseudomonas mendocina	N-succinyl-L-glutamate 5-semialdehyde + L-glutamate	-	?
N2-succinyl-L-ornithine + 2-oxoglutarate	-	Burkholderia cepacia	N-succinyl-L-glutamate 5-semialdehyde + L-glutamate	-	?
N2-succinyl-L-ornithine + 2-oxoglutarate	-	Vogesella indigofera	N-succinyl-L-glutamate 5-semialdehyde + L-glutamate	-	?
N2-succinyl-L-ornithine + 2-oxoglutarate	-	Oceanimonas doudoroffii	N-succinyl-L-glutamate 5-semialdehyde + L-glutamate	-	?
N2-succinyl-L-ornithine + 2-oxoglutarate	-	Pseudomonas chlororaphis subsp. aureofaciens	N-succinyl-L-glutamate 5-semialdehyde + L-glutamate	-	?
N2-succinyl-L-ornithine + 2-oxoglutarate	-	Trinickia caryophylli	N-succinyl-L-glutamate 5-semialdehyde + L-glutamate	-	?
N2-succinyl-L-ornithine + 2-oxoglutarate	-	Pseudomonas formicans	N-succinyl-L-glutamate 5-semialdehyde + L-glutamate	-	?
N2-succinyl-L-ornithine + 2-oxoglutarate	key enzyme in the group of pdx gene-encoded enzymes involved in the de novo synthesis of vitamin B6	Burkholderia cepacia	N-succinyl-L-glutamate 5-semialdehyde + L-glutamate	-	?
N2-succinyl-L-ornithine + 2-oxoglutarate	step in metabolic conversion of L-arginine into L-glutamate, pathway succinylornithine and competing pathways overview	Pseudomonas fluorescens	N-succinyl-L-glutamate 5-semialdehyde + L-glutamate	-	?
N2-succinyl-L-ornithine + 2-oxoglutarate	step in metabolic conversion of L-arginine into L-glutamate, pathway succinylornithine and competing pathways overview	Pseudomonas aeruginosa	N-succinyl-L-glutamate 5-semialdehyde + L-glutamate	-	?
N2-succinyl-L-ornithine + 2-oxoglutarate	step in metabolic conversion of L-arginine into L-glutamate, pathway succinylornithine and competing pathways overview	Pseudomonas putida	N-succinyl-L-glutamate 5-semialdehyde + L-glutamate	-	?
N2-succinyl-L-ornithine + 2-oxoglutarate	step in metabolic conversion of L-arginine into L-glutamate, pathway succinylornithine and competing pathways overview	Pseudomonas mendocina	N-succinyl-L-glutamate 5-semialdehyde + L-glutamate	-	?
N2-succinyl-L-ornithine + 2-oxoglutarate	step in metabolic conversion of L-arginine into L-glutamate, pathway succinylornithine and competing pathways overview	Pseudomonas chlororaphis subsp. aureofaciens	N-succinyl-L-glutamate 5-semialdehyde + L-glutamate	-	?
N2-succinyl-L-ornithine + 2-oxoglutarate	step in metabolic conversion of L-arginine into L-glutamate, pathway succinylornithine and competing pathways overview	Trinickia caryophylli	N-succinyl-L-glutamate 5-semialdehyde + L-glutamate	-	?
N2-succinyl-L-ornithine + 2-oxoglutarate	step in metabolic conversion of L-arginine into L-glutamate, succinylornithine pathway and competing pathways, overview	Pseudomonas aeruginosa	N-succinyl-L-glutamate 5-semialdehyde + L-glutamate	-	?
N2-succinyl-L-ornithine + 2-oxoglutarate	step in metabolic conversion of L-arginine into L-glutamate, succinylornithine pathway and competing pathways, overview	Vogesella indigofera	N-succinyl-L-glutamate 5-semialdehyde + L-glutamate	-	?
N2-succinyl-L-ornithine + 2-oxoglutarate	step in metabolic conversion of L-arginine into L-glutamate, succinylornithine pathway and competing pathways, overview	Oceanimonas doudoroffii	N-succinyl-L-glutamate 5-semialdehyde + L-glutamate	-	?
N2-succinyl-L-ornithine + 2-oxoglutarate	step in metabolic conversion of L-arginine into L-glutamate, succinylornithine pathway and competing pathways, overview	Pseudomonas formicans	N-succinyl-L-glutamate 5-semialdehyde + L-glutamate	-	?

Synonyms

Synonyms	Comment	Organism
SOAT	-	Pseudomonas fluorescens
SOAT	-	Pseudomonas aeruginosa
SOAT	-	Pseudomonas putida
SOAT	-	Pseudomonas mendocina
SOAT	-	Burkholderia cepacia
SOAT	-	Vogesella indigofera
SOAT	-	Oceanimonas doudoroffii
SOAT	-	Pseudomonas chlororaphis subsp. aureofaciens
SOAT	-	Trinickia caryophylli
SOAT	-	Pseudomonas formicans
succinylornithine aminotransferase	-	Pseudomonas fluorescens
succinylornithine aminotransferase	-	Pseudomonas aeruginosa
succinylornithine aminotransferase	-	Pseudomonas putida
succinylornithine aminotransferase	-	Pseudomonas mendocina
succinylornithine aminotransferase	-	Burkholderia cepacia
succinylornithine aminotransferase	-	Vogesella indigofera
succinylornithine aminotransferase	-	Oceanimonas doudoroffii
succinylornithine aminotransferase	-	Pseudomonas chlororaphis subsp. aureofaciens
succinylornithine aminotransferase	-	Trinickia caryophylli
succinylornithine aminotransferase	-	Pseudomonas formicans

Temperature Optimum [°C]

Temperature Optimum [°C]	Temperature Optimum Maximum [°C]	Comment	Organism
37	-	assay at	Pseudomonas fluorescens
37	-	assay at	Pseudomonas aeruginosa
37	-	assay at	Pseudomonas putida
37	-	assay at	Pseudomonas mendocina
37	-	assay at	Burkholderia cepacia
37	-	assay at	Vogesella indigofera
37	-	assay at	Oceanimonas doudoroffii
37	-	assay at	Pseudomonas chlororaphis subsp. aureofaciens
37	-	assay at	Trinickia caryophylli
37	-	assay at	Pseudomonas formicans

pH Optimum

pH Optimum Minimum	pH Optimum Maximum	Comment	Organism
8.5	-	assay at	Pseudomonas fluorescens
8.5	-	assay at	Pseudomonas aeruginosa
8.5	-	assay at	Pseudomonas putida
8.5	-	assay at	Pseudomonas mendocina
8.5	-	assay at	Burkholderia cepacia
8.5	-	assay at	Vogesella indigofera
8.5	-	assay at	Oceanimonas doudoroffii
8.5	-	assay at	Pseudomonas chlororaphis subsp. aureofaciens
8.5	-	assay at	Trinickia caryophylli
8.5	-	assay at	Pseudomonas formicans

Cofactor

Cofactor	Comment	Organism
pyridoxal 5'-phosphate	-	Pseudomonas fluorescens
pyridoxal 5'-phosphate	-	Pseudomonas aeruginosa
pyridoxal 5'-phosphate	-	Pseudomonas putida
pyridoxal 5'-phosphate	-	Pseudomonas mendocina
pyridoxal 5'-phosphate	-	Burkholderia cepacia
pyridoxal 5'-phosphate	-	Vogesella indigofera
pyridoxal 5'-phosphate	-	Oceanimonas doudoroffii
pyridoxal 5'-phosphate	-	Pseudomonas chlororaphis subsp. aureofaciens
pyridoxal 5'-phosphate	-	Trinickia caryophylli
pyridoxal 5'-phosphate	-	Pseudomonas formicans