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Literature summary for 2.6.1.7 extracted from
- Quantum mechanics/molecular mechanics (QM/MM) modeling of the irreversible transamination of L-kynurenine to kynurenic acid: the round dance of kynurenine aminotransferase II (2009), Biochim. Biophys. Acta, 1794, 1802-1812.
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| L-kynurenine + 2-oxobutyrate | - |
Homo sapiens | kynurenic acid + 2-aminobutanoate + H2O | - |
? |  |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| homodimer | x-ray crystallography | Homo sapiens |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| KAT-II | isoform | Homo sapiens |
| kynurenine aminotransferase II | - |
Homo sapiens |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| pyridoxal 5'-phosphate | - |
Homo sapiens | |
General Information
| General Information | Comment | Organism |
|---|---|---|
| physiological function | KAT-II is the enzymatic isoform that mainly accounts for the synthesis of cerebral kynurenic acid | Homo sapiens |
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Release 2023.1 (January 2023)
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