BRENDA - Enzyme Database show
show all sequences of 2.6.1.64

Glutamine transaminase K from rat kidney

Cooper, A.J.L.; Meister, A.; Methods Enzymol. 113, 344-349 (1985)

Data extracted from this reference:

Localization
Localization
Commentary
Organism
GeneOntology No.
Textmining
cytoplasm
-
Rattus norvegicus
5737
-
mitochondrion
-
Rattus norvegicus
5739
-
Natural Substrates/ Products (Substrates)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
L-glutamine + phenylpyruvate
Rattus norvegicus
-
2-oxoglutaramate + L-phenylalanine
-
Rattus norvegicus
r
L-glutamine + phenylpyruvate
Rattus norvegicus Wistar
-
2-oxoglutaramate + L-phenylalanine
-
Rattus norvegicus Wistar
r
Organism
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
Rattus norvegicus
-
Wistar
-
Rattus norvegicus Wistar
-
Wistar
-
Purification (Commentary)
Commentary
Organism
-
Rattus norvegicus
Source Tissue
Source Tissue
Commentary
Organism
Textmining
brain
-
Rattus norvegicus
-
kidney
-
Rattus norvegicus
-
liver
-
Rattus norvegicus
-
Specific Activity [micromol/min/mg]
Specific Activity Minimum [µmol/min/mg]
Specific Activity Maximum [µmol/min/mg]
Commentary
Organism
2.65
-
mitochondrial isozyme
Rattus norvegicus
6.48
-
cytoplasmic isozyme
Rattus norvegicus
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
L-glutamine + glyoxylate
-
640175
Rattus norvegicus
2-oxoglutaramate + glycine
-
-
-
r
L-glutamine + glyoxylate
-
640175
Rattus norvegicus Wistar
2-oxoglutaramate + glycine
-
-
-
r
L-glutamine + phenylpyruvate
-
640175
Rattus norvegicus
2-oxoglutaramate + L-phenylalanine
-
640175
Rattus norvegicus
r
L-glutamine + phenylpyruvate
-
640175
Rattus norvegicus Wistar
2-oxoglutaramate + L-phenylalanine
-
640175
Rattus norvegicus Wistar
r
L-glutamine + pyruvate
-
640175
Rattus norvegicus
2-oxoglutaramate + L-alanine
-
640175
Rattus norvegicus
r
L-glutamine + pyruvate
-
640175
Rattus norvegicus Wistar
2-oxoglutaramate + L-alanine
-
640175
Rattus norvegicus Wistar
r
L-phenylalanine + 4-(methylsulfanyl)-2-oxobutanoate
-
640175
Rattus norvegicus
phenylpyruvate + L-methionine
-
-
-
r
L-phenylalanine + 4-(methylsulfanyl)-2-oxobutanoate
-
640175
Rattus norvegicus Wistar
phenylpyruvate + L-methionine
-
-
-
r
Localization (protein specific)
Localization
Commentary
Organism
GeneOntology No.
Textmining
cytoplasm
-
Rattus norvegicus
5737
-
mitochondrion
-
Rattus norvegicus
5739
-
Natural Substrates/ Products (Substrates) (protein specific)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
L-glutamine + phenylpyruvate
Rattus norvegicus
-
2-oxoglutaramate + L-phenylalanine
-
Rattus norvegicus
r
L-glutamine + phenylpyruvate
Rattus norvegicus Wistar
-
2-oxoglutaramate + L-phenylalanine
-
Rattus norvegicus Wistar
r
Purification (Commentary) (protein specific)
Commentary
Organism
-
Rattus norvegicus
Source Tissue (protein specific)
Source Tissue
Commentary
Organism
Textmining
brain
-
Rattus norvegicus
-
kidney
-
Rattus norvegicus
-
liver
-
Rattus norvegicus
-
Specific Activity [micromol/min/mg] (protein specific)
Specific Activity Minimum [µmol/min/mg]
Specific Activity Maximum [µmol/min/mg]
Commentary
Organism
2.65
-
mitochondrial isozyme
Rattus norvegicus
6.48
-
cytoplasmic isozyme
Rattus norvegicus
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
L-glutamine + glyoxylate
-
640175
Rattus norvegicus
2-oxoglutaramate + glycine
-
-
-
r
L-glutamine + glyoxylate
-
640175
Rattus norvegicus Wistar
2-oxoglutaramate + glycine
-
-
-
r
L-glutamine + phenylpyruvate
-
640175
Rattus norvegicus
2-oxoglutaramate + L-phenylalanine
-
640175
Rattus norvegicus
r
L-glutamine + phenylpyruvate
-
640175
Rattus norvegicus Wistar
2-oxoglutaramate + L-phenylalanine
-
640175
Rattus norvegicus Wistar
r
L-glutamine + pyruvate
-
640175
Rattus norvegicus
2-oxoglutaramate + L-alanine
-
640175
Rattus norvegicus
r
L-glutamine + pyruvate
-
640175
Rattus norvegicus Wistar
2-oxoglutaramate + L-alanine
-
640175
Rattus norvegicus Wistar
r
L-phenylalanine + 4-(methylsulfanyl)-2-oxobutanoate
-
640175
Rattus norvegicus
phenylpyruvate + L-methionine
-
-
-
r
L-phenylalanine + 4-(methylsulfanyl)-2-oxobutanoate
-
640175
Rattus norvegicus Wistar
phenylpyruvate + L-methionine
-
-
-
r
Other publictions for EC 2.6.1.64
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Temperature Optimum [°C]
Temperature Range [°C]
Temperature Stability [°C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [°C] (protein specific)
Temperature Range [°C] (protein specific)
Temperature Stability [°C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
721432
Bridges
New insights into the metaboli ...
Homo sapiens
Arch. Biochem. Biophys.
517
20-29
2012
-
-
1
-
-
-
4
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
5
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
4
-
-
-
-
-
-
-
-
-
-
-
-
-
-
5
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
684716
Cooper
Substrate specificity of human ...
Homo sapiens
Arch. Biochem. Biophys.
474
72-81
2008
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
15
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
15
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
662198
Goto
Crystal structures of glutamin ...
Thermus thermophilus, Thermus thermophilus HB8 / ATCC 27634 / DSM 579
J. Biol. Chem.
279
16518-16525
2004
-
-
-
1
-
-
-
-
-
-
-
-
-
90
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
636642
Mosca
Tissue expression and translat ...
Rattus norvegicus
Biochim. Biophys. Acta
1628
1-10
2003
-
-
1
-
-
-
-
-
2
-
-
1
-
2
-
-
-
-
-
1
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
2
-
-
1
-
-
-
-
-
1
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
662056
Hosono
Glutamine:phenylpyruvate amino ...
Thermus thermophilus, Thermus thermophilus HB8 / ATCC 27634 / DSM 579
J. Biochem.
134
843-851
2003
-
-
1
-
-
-
-
21
-
-
3
-
-
90
-
-
-
-
-
-
-
-
23
1
-
-
-
21
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
21
-
-
3
-
-
-
-
-
-
-
-
-
23
1
-
-
-
21
-
-
-
-
-
-
-
-
-
-
640184
Han
Kynurenine aminotransferase an ...
Escherichia coli
Biochem. J.
360
617-623
2001
-
-
1
-
-
-
-
-
-
-
-
-
-
1
-
-
1
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
640183
Commandeur
Bioactivation of selenocystein ...
Rattus norvegicus
J. Pharmacol. Exp. Ther.
294
753-761
2000
-
-
-
-
-
-
3
-
1
-
2
-
-
2
-
-
1
-
-
2
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
3
-
-
1
-
2
-
-
-
-
1
-
2
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
640182
Trevisan
Glutamine transaminase K intra ...
Rattus norvegicus
Arch. Toxicol.
72
531-535
1998
-
-
-
-
-
-
-
-
1
-
1
-
-
1
-
-
-
-
-
3
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
1
-
-
-
-
-
-
-
1
-
1
-
-
-
-
-
-
3
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
640181
Abraham
Cloning and expression of a ra ...
Rattus norvegicus
Arch. Biochem. Biophys.
335
311-320
1996
-
-
1
-
-
-
-
-
1
-
4
1
-
1
-
-
1
-
-
1
1
-
3
1
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
1
-
4
1
-
-
-
1
-
1
1
-
3
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
636626
Malherbe
Identification of a mitochondr ...
Rattus norvegicus
FEBS Lett.
367
141-144
1995
-
-
1
-
-
-
-
-
3
-
-
-
-
2
-
-
-
-
-
2
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
3
-
-
-
-
-
-
-
-
2
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
640179
Abraham
Glutamine transaminase K is no ...
Rattus norvegicus
Mol. Pharmacol.
48
855-860
1995
-
-
-
-
-
-
-
-
2
-
2
-
-
1
-
-
1
-
-
1
1
-
1
1
-
-
-
-
-
-
-
1
-
-
-
-
-
-
1
-
-
-
-
-
-
-
2
-
2
-
-
-
-
1
-
1
1
-
1
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
288890
Makar
Glutamine transaminase K and o ...
Gallus gallus, Homo sapiens, Mus musculus, Rattus norvegicus
J. Neurochem.
62
1983-1988
1994
-
-
-
-
-
-
-
-
3
-
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2
-
4
-
-
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-
-
11
-
-
4
-
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-
-
-
-
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-
-
-
-
-
-
-
-
-
-
-
-
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-
3
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2
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-
-
11
-
-
4
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
640177
Wu
-
Glutamine metabolism in skelet ...
Gallus gallus, Gallus gallus Hubbard, Rattus norvegicus, Rattus norvegicus Buffalo
Biochem. J.
274
769-774
1991
-
-
-
-
-
-
-
-
3
-
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2
-
4
-
-
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-
-
2
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6
-
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-
-
-
-
-
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3
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2
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-
-
2
-
-
6
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
640176
Ricci
The transamination of L-cystat ...
Bos taurus
Eur. J. Biochem.
157
57-63
1986
-
-
-
-
-
1
-
5
-
-
2
-
-
1
-
-
1
-
-
1
-
1
21
1
-
-
-
-
1
-
-
1
-
-
-
-
-
-
1
-
-
1
-
-
-
5
-
-
2
-
-
-
-
1
-
1
-
1
21
1
-
-
-
-
1
-
-
-
-
-
-
-
-
-
640175
Cooper
Glutamine transaminase K from ...
Rattus norvegicus, Rattus norvegicus Wistar
Methods Enzymol.
113
344-349
1985
-
-
-
-
-
-
-
-
2
-
-
2
-
166
-
-
1
-
-
3
2
-
8
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
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2
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2
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-
1
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3
2
-
8
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
640174
Cooper
Purification of soluble and mi ...
Rattus norvegicus, Rattus norvegicus Wistar
Anal. Biochem.
89
451-460
1978
-
-
-
-
-
-
-
-
2
-
2
2
-
166
-
-
1
-
-
4
2
1
6
1
-
-
-
-
-
-
-
1
-
-
-
-
-
-
1
-
-
-
-
-
-
-
2
-
2
2
-
-
-
1
-
4
2
1
6
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
640173
Noguchi
Identity of rat kidney histidi ...
Rattus norvegicus, Rattus norvegicus Donryu
Biochem. J.
161
177-179
1977
-
-
-
-
-
-
4
-
-
-
-
-
-
9
-
-
1
-
-
5
2
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
4
-
-
-
-
-
-
-
-
-
1
-
5
2
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
640172
Van Leuven
Glutamine transaminase from br ...
Rattus norvegicus
Eur. J. Biochem.
65
271-274
1976
-
-
-
-
-
-
-
17
-
-
-
1
-
1
-
-
1
-
-
1
-
-
34
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
17
-
-
-
1
-
-
-
1
-
1
-
-
34
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
640171
Van Leuven
Highly purified glutamine tran ...
Rattus norvegicus
Eur. J. Biochem.
58
153-158
1975
-
-
-
-
-
2
3
2
-
-
2
1
-
1
-
-
1
-
-
1
1
-
6
1
-
-
1
-
1
1
-
1
-
-
-
-
-
-
1
-
-
2
-
3
-
2
-
-
2
1
-
-
-
1
-
1
1
-
6
1
-
-
1
-
1
1
-
-
-
-
-
-
-
-
639901
Cooper
Isolation and properties of a ...
Rattus norvegicus, Rattus norvegicus Sprague-Dawley
J. Biol. Chem.
249
2554-2561
1974
-
-
-
-
-
-
-
11
1
-
2
-
-
162
-
-
1
-
-
5
1
-
55
1
-
-
1
-
-
-
-
1
-
-
-
-
-
-
1
-
-
-
-
-
-
11
1
-
2
-
-
-
-
1
-
5
1
-
55
1
-
-
1
-
-
-
-
-
-
-
-
-
-
-