Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 2.6.1.57 extracted from

  • Fadnavis, N.W.; Seo, S.; Seo, J.; Kim, B.
    Asymmetric synthesis of nonproteinogenic amino acids with L-amino acid transaminase: Synthesis of (2S)-2-amino-4-oxo-4-phenylbutyric and (3E,2S)-2-amino-4-phenylbutenoic acid (2006), Tetrahedron, 17, 2199-2202.
No PubMed abstract available
Search for more literature for 2.6.1.57

Application

Application Comment Organism
synthesis asymmetric synthesis of the nonproteinogenic amino acids (2S)-2-amino-4-oxo-4-phenylbutyric and (3E,2S)-2-amino-4-phenylbutenoic acid by recombinant Escherichia coli whole cells overexpressing aromatic transaminase from Enterobacter sp. BK2K-1 (AroATEs) in high yields (68–78%) and high enantiomeric purity (>99%) using L-aspartic acid as an amino donor Enterobacter sp.

Cloned(Commentary)

Cloned (Comment) Organism
expression in Escherichia coli Enterobacter sp.

Organism

Organism UniProt Comment Textmining
Enterobacter sp.
-
-
-
Enterobacter sp. BK2K-1
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2,4-dioxo-4-phenylbutyric acid + L-Asp
-
 Enterobacter sp. (2S)-2-amino-4-oxo-4-phenylbutyric acid + oxaloacetate
-
 ?
2,4-dioxo-4-phenylbutyric acid + L-Asp
-
 Enterobacter sp. BK2K-1 (2S)-2-amino-4-oxo-4-phenylbutyric acid + oxaloacetate
-
 ?
2-oxo-4-phenylbut-3-enoic acid + L-Asp
-
 Enterobacter sp. (3E,2S)-2-amino-4-phenylbutenoic acid + oxaloacetate
-
 ?
2-oxo-4-phenylbut-3-enoic acid + L-Asp
-
 Enterobacter sp. BK2K-1 (3E,2S)-2-amino-4-phenylbutenoic acid + oxaloacetate
-
 ?

Synonyms

Synonyms Comment Organism
AroATEs
-
 Enterobacter sp.