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Literature summary for 2.6.1.45 extracted from
- Detection of intermediates in reactions catalyzed by PLP-dependent enzymes: O-acetylserine sulfhydrylase and serine-glyoxalate aminotransferase (2002), Methods Enzymol., 354, 223-237.
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| L-serine + glyoxylate | Hyphomicrobium methylovorum | part of the C-1 assimilation pathway | 3-hydroxypyruvate + glycine | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Hyphomicrobium methylovorum | - |
- |
- |
Reaction
| Reaction | Comment | Organism | Reaction ID |
|---|---|---|---|
| L-serine + glyoxylate = 3-hydroxypyruvate + glycine | ping-pong reaction mechanism | Hyphomicrobium methylovorum | |
| L-serine + glyoxylate = 3-hydroxypyruvate + glycine | reaction is catalyzed via the initial formation of an external Schiff base intermediate | Hyphomicrobium methylovorum |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| L-serine + glyoxylate | part of the C-1 assimilation pathway | Hyphomicrobium methylovorum | 3-hydroxypyruvate + glycine | - |
? | |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| pyridoxal 5'-phosphate | - |
Hyphomicrobium methylovorum | |
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Release 2023.1 (January 2023)
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