Cloned (Comment) | Organism |
---|---|
expressed in COS-7 cells and human umbilical vein endothelial cells with a C-terminal FLAG epitope tag | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
mitochondrion | - |
Homo sapiens | 5739 | - |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
52000 | - |
FLAG-tagged enzyme, SDS-PAGE | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
kidney | expressed primarily in the kidney | Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-alanine + glyoxylate | - |
Homo sapiens | pyruvate + glycine | - |
? | |
additional information | mitochondrially localized human AGXT2 is able to effectively metabolize asymmetric dimethylarginine in vivo | Homo sapiens | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
AGXT2 | - |
Homo sapiens |
alanine-glyoxylate aminotransferase 2 | - |
Homo sapiens |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
pyridoxal 5'-phosphate | - |
Homo sapiens |
General Information | Comment | Organism |
---|---|---|
physiological function | overexpression of human AGXT2 protects from asymmetric dimethylarginine-induced inhibition in nitric oxide production | Homo sapiens |